Kedi FIPV için GS-441524

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Ürün adı:GS-441524 Kullanım:cat fipv Sıvı:20mg/ml,30mg/ml 6ml/şişe, 7ml/şişe,8ml/şişe, 10ml/şişe Hap:5mg,10mg,20mg,25mg,40mg,50mg,60mg başına hap veya müşteri gereksinimlerine göre.

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Detaylar

Etiketler

Ürün adı	Gs441524
Dış görünüş	White powder,pill,liquid type
Tahlil	>99%
Ölçek	HPLC
CAS	1191237-69-0
MF	C12H13N5O4
Depolama sıcaklığı	Serin Kuru Yer

giriiş
GS-441524, Remdesivir'in biyolojik olarak aktif bileşenidir ve 18 aydan uzun bir süredir kedileri kedi bulaşıcı peritonitinden (FlP) güvenli ve etkili bir şekilde tedavi etmek için dünya çapında yaygın olarak kullanılmaktadır. FIP, kedilerin yaygın ve oldukça ölümcül bir hastalığıdır.

İşlev
GS-441524, birçok RNA virüsüne karşı güçlü antiviral aktivite gösteren, bilimsel adı nükleosit trifosfat rekabetçi inhibitörü olan küçük bir moleküldür. Viral RNA'ya bağımlı RNA polimeraz için alternatif bir substrat ve RNA zinciri sonlandırıcı olarak hizmet eder. GS-441524'ün kedi hücrelerinde toksik olmayan konsantrasyonu 100 kadar yüksektir, bu da CRFK hücre kültüründe FIPV replikasyonunu ve 1 kadar düşük bir konsantrasyonla doğal olarak enfekte olmuş kedi peritoneal makrofajlarını etkili bir şekilde inhibe eder.

gs-441524 for white liquid type factories

S: GS nedir?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Oral versiyon henüz yaygın olarak bulunmasa da, şu anda bir enjeksiyon veya oral ilaç olarak mevcuttur. Lütfen bir yöneticiye sorun!
S: Tedavi ne kadar sürer?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.

Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:

gs-441524 for white liquid type factory

S: GS enjeksiyonlarını nasıl yaparım?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet

gs-441524 for white liquid type manufacturer

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