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Produktnavn |
Gs441524 |
Utseende |
White powder,pill,liquid type |
Assay |
>99 % |
Test |
HPLC |
CAS |
1191237-69-0 |
MF |
C12H13N5O4 |
Lager temperatur |
Kjølt tørt sted |
Introduksjon
GS-441524 er den biologisk aktive komponenten i Remdesivir og har blitt mye brukt over hele verden for å trygt og effektivt kurere katter av infeksiøs peritonitt hos katter (FlP) i over 18 måneder. FIP er en vanlig og svært dødelig sykdom hos katter.
Funksjon
GS-441524 er et lite molekyl med et vitenskapelig navn på nukleosidtrifosfat-konkurransehemmer, som viser sterk antiviral aktivitet mot mange RNA-virus. Den fungerer som et alternativt substrat og RNA-kjedeterminator for viral RNA-avhengig RNA-polymerase. Den ikke-toksiske konsentrasjonen av GS-441524 i katteceller er så høy som 100, noe som effektivt hemmer FIPV-replikasjon i CRFK-cellekultur og naturlig infiserte katteperitoneale makrofager med en konsentrasjon så lav som 1.
Spørsmål: Hva er GS?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Det er for tiden tilgjengelig som en injeksjon eller en oral medisin, selv om den orale versjonen fortsatt ikke er allment tilgjengelig ennå. Spør en admin!
Spørsmål: Hvor lang er behandlingen?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
Spørsmål: Hvordan gir jeg GS-injeksjonene?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
Pakking:
- med pose eller kartong
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In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
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