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nombre del producto |
gs441524 |
Apariencia |
White powder,pill,liquid type |
Ensayo |
>99% |
Prueba |
HPLC |
CAS |
1191237-69-0 |
FM |
C12H13N5O4 |
Temperatura de almacenamiento |
Lugar fresco y seco |
Introducción
GS-441524 es el componente biológicamente activo de Remdesivir y se ha utilizado ampliamente en todo el mundo para curar de forma segura y eficaz a los gatos de la peritonitis infecciosa felina (FlP) durante más de 18 meses. La FIP es una enfermedad común y altamente fatal de los gatos.
Función
GS-441524 es una molécula pequeña con un nombre científico de inhibidor competitivo de trifosfato de nucleósido, que muestra una fuerte actividad antiviral contra muchos virus de ARN. Sirve como sustrato alternativo y terminador de la cadena de ARN para la ARN polimerasa dependiente de ARN viral. La concentración no tóxica de GS-441524 en células felinas es de hasta 100, lo que inhibe eficazmente la replicación de FIPV en cultivos de células CRFK y macrófagos peritoneales de gatos infectados naturalmente con una concentración tan baja como 1.
P: ¿Qué es GS?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Actualmente está disponible como inyección o como medicamento oral, aunque la versión oral aún no está ampliamente disponible. ¡Pregúntale a un administrador!
P: ¿Cuánto dura el tratamiento?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
P: ¿Cómo administro las inyecciones de GS?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
Embalaje:
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PD: aceptamos la personalización del embalaje.
Envío:
Enviamos productos a través de DHL, Fedex, UPS, TNT, China post, NL Post y otros servicios de mensajería, con un peso de 10 g a 1000 kg o incluso a granel.
Shipping details & shipping documents will be provided and sent to customers as long as it is ready.
Seguimos rastreando el envío hasta que los clientes lo reciban bien.
After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safety and efficiently.
1kg/foil bag, 25kg/bag or drum (PV bag for inner packing, and aluminium foil bag for outer packing.)
20 tons/20ft container,
25 tons/40ft container,
Or follow the client's requirements.
Delivery : We have special line transportation, or we can give it to yourforwarder Our special line transport is to ensure safe delivery to yourdesignated location, can be free of customs clearance (FedEx /EMS UPSDHL/TNT)
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Package:To better ensure thesafety of your goods, professionalenvironmentally friendly, convenient and efficient packaging services will beprovided.(1kg/25kgs/160kgs/200kgs)
Hebei Weimiao Import and Export Trade Co., Ltd.is specialized inR&D, manufacturingand marketing APIS,pharmaceuticalintermediates, we have two affiliated manufacturers. More than 70percent products are exported to Europe,America, Japan and Southeast Asia.Our factory located in Hebei, a beautiful coastal cityin the east region of China.
In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
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PRE-SALES
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2.quality assurance We can provide you with the test report of theproduct
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