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Product Name |
Gs441524 |
Aspectus |
White powder,pill,liquid type |
Assay |
>99% |
Test |
HPLC |
CAS |
1191237-69-0 |
MF |
C12H13N5O4 |
Repono Temperature |
Frigus siccum |
Introductio
GS-441524 biologice activum Remdesiviri elementum est et circum orbem terrarum late adhibitum est ut felices felines infectiosis peritonitis (FlP) per 18 menses tuto et efficaciter sanarent. FIP communis et valde letalis morbus felium est.
Officium
GS-441524 Moleculum parvum est cum nomine scientifico inhibitoris nucleosidi triphosphatae competitive, quae validam actionem antiviralem contra multos RNA virus ostendit. Alterum subiectum inservit ac RNA terminator catenae viralis RNA dependens polymerase RNA. Concentratio non-toxica GS-441524 in cellulis felinis tam alta est quam 100, quae efficaciter replicationem in CRFK cellae culturae FIPV vetat et naturaliter infectas cat peritonaeas macrophages cum retentione tam humilis quam 1 .
Q: Quid est GS?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
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Q: Quousque curatio est?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
Q: Quomodo do injectiones GS?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
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