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שם מוצר |
Gs441524 |
מראה חיצוני |
White powder,pill,liquid type |
בדיקה |
>99% |
מִבְחָן |
HPLC |
CAS |
1191237-69-0 |
MF |
C12H13N5O4 |
טמפרטורת אחסון |
מקום יבש קריר |
מבוא
GS-441524 הוא הרכיב הפעיל ביולוגית של Remdesivir ונמצא בשימוש נרחב ברחבי העולם לריפוי בטוח ויעיל של חתולים של דלקת צפק זיהומית חתולית (FlP) במשך למעלה מ-18 חודשים. FIP היא מחלה נפוצה וקטלנית ביותר של חתולים.
פוּנקצִיָה
GS-441524 היא מולקולה קטנה בעלת שם מדעי של מעכב תחרותי נוקלאוזיד טריפוספט, אשר מראה פעילות אנטי-ויראלית חזקה כנגד נגיפי RNA רבים. הוא משמש כמצע חלופי ומסיים שרשרת RNA לפולימראז RNA תלוי RNA ויראלי. הריכוז הלא-רעיל של GS-441524 בתאי חתולים גבוה עד 100, מה שמעכב ביעילות את שכפול FIPV בתרבית תאי CRFK ומקרופאגים צפקיים של חתולים נגועים באופן טבעי בריכוז נמוך כמו 1.
ש: מה זה GS?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
זה זמין כעת כזריקה או כתרופה דרך הפה למרות שהגרסה האוראלית עדיין לא זמינה באופן נרחב. נא לשאול מנהל!
ש: כמה זמן הטיפול?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
ש: איך אני נותן את זריקות ה-GS?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
אֲרִיזָה:
- על ידי שקית או קופסא קרטון
נ.ב: אנו מקבלים התאמה אישית של אריזה.
משלוח:
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Shipping details & shipping documents will be provided and sent to customers as long as it is ready.
אנו ממשיכים לעקוב אחר המשלוח עד שהלקוחות יתקבלו היטב.
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In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
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