GS-441524 Cat FIPV

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Produkta nosaukums: GS-441524 Lietošana: kaķu fipv šķidrums: 20mg/ml, 30mg/ml 6ml/flakons, 7ml/flakons,8ml/flakons,10ml/flakons Tabletes:5mg,10mg,20mg,25mg,40mg,50mg uz 60mg tabletes vai atbilstoši klienta prasībām.

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Sīkāka informācija

Tagi

produkta nosaukums	Gs441524
Izskats	White powder,pill,liquid type
Pārbaude	>99%
Pārbaude	HPLC
CAS	1191237-69-0
MF	C12H13N5O4
Uzglabāšanas temperatūra	Vēsa, sausa vieta

Ievads
GS-441524 ir Remdesivir bioloģiski aktīvā sastāvdaļa, un to plaši izmanto visā pasaulē, lai droši un efektīvi izārstētu kaķus no kaķu infekciozā peritonīta (FlP) vairāk nekā 18 mēnešus. FIP ir izplatīta un ļoti letāla kaķu slimība.

Funkcija
GS-441524 ir maza molekula ar zinātnisku nosaukumu nukleozīdu trifosfātu konkurētspējīgs inhibitors, kas uzrāda spēcīgu pretvīrusu aktivitāti pret daudziem RNS vīrusiem. Tas kalpo kā alternatīvs substrāts un RNS ķēdes terminators vīrusa RNS atkarīgajai RNS polimerāzei. GS-441524 netoksiskā koncentrācija kaķu šūnās ir pat 100, kas efektīvi inhibē FIPV replikāciju CRFK šūnu kultūrā un dabiski inficētos kaķu peritoneālos makrofāgos ar koncentrāciju līdz 1.

gs-441524 for white liquid type factories

J: Kas ir GS?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Pašlaik tas ir pieejams kā injekcijas vai perorāls medikaments, lai gan iekšķīgi lietojamā versija vēl joprojām nav plaši pieejama. Lūdzu, jautājiet administratoram!
J: Cik ilga ir ārstēšana?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.

Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:

gs-441524 for white liquid type factory

J: Kā veikt GS injekcijas?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet

gs-441524 for white liquid type manufacturer

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1kg/foil bag, 25kg/bag or drum (PV bag for inner packing, and aluminium foil bag for outer packing.)
20 tons/20ft container,
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