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Ainm Táirge |
Gs441524 |
Dealramh |
White powder,pill,liquid type |
Measúnacht |
>99% |
Scrúdú |
HPLC |
CAS |
1191237-69-0 |
MF |
C12H13N5O4 |
Teocht Stórála |
Áit Thirim Fhionnuar |
Réamhrá
Is é GS-441524 an chomhpháirt atá gníomhach go bitheolaíoch de Remdesivir agus baineadh úsáid as go forleathan ar fud an domhain chun cait a leigheas go sábháilte agus go héifeachtach ar peritonitis ionfhabhtaíoch feline (FlP) le breis agus 18 mí. Is galar coitianta agus an-mharfach é FIP ar chait.
Feidhm
Is móilín beag é GS-441524 le ainm eolaíoch inhibitor iomaíoch nucleoside triphosphate, a léiríonn gníomhaíocht antiviral láidir i gcoinne go leor víris RNA. Feidhmíonn sé mar shubstráit eile agus mar chríochnóir slabhra RNA le haghaidh polaiméaráise víreasach RNA-spleách RNA. Tá an tiúchan neamh-tocsaineach de GS-441524 i gcealla feline chomh hard le 100, rud a chuireann bac go héifeachtach ar mhacasamhlú FIPV i gcultúr cille CRFK agus macrophages peritoneal cat atá ionfhabhtaithe go nádúrtha le tiúchan chomh híseal agus 1.
C: Cad é GS?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Tá sé ar fáil faoi láthair mar instealladh nó mar chógas ó bhéal cé nach bhfuil an leagan béil ar fáil go forleathan go fóill. Iarr ar riarthóir le do thoil!
C: Cé chomh fada is atá an chóireáil?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
C: Conas a thugann mé na instealltaí GS?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
Pacáil:
- le mála nó bosca cartán
PS: glacaimid le saincheaptha pacáistithe.
Á sheoladh:
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After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safety and efficiently.
1kg/foil bag, 25kg/bag or drum (PV bag for inner packing, and aluminium foil bag for outer packing.)
20 tons/20ft container,
25 tons/40ft container,
Or follow the client's requirements.
Delivery : We have special line transportation, or we can give it to yourforwarder Our special line transport is to ensure safe delivery to yourdesignated location, can be free of customs clearance (FedEx /EMS UPSDHL/TNT)
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In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
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