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Nom du produit |
Gs441524 |
Apparence |
White powder,pill,liquid type |
Essai |
>99% |
Test |
CLHP |
CAS |
1191237-69-0 |
MF |
C12H13N5O4 |
Température de stockage |
Endroit frais et sec |
Introduction
Le GS-441524 est le composant biologiquement actif du Remdesivir et a été largement utilisé dans le monde entier pour guérir efficacement et en toute sécurité les chats de la péritonite infectieuse féline (FlP) pendant plus de 18 mois. La PIF est une maladie courante et très mortelle des chats.
Fonction
Le GS-441524 est une petite molécule portant le nom scientifique d'inhibiteur compétitif du nucléoside triphosphate, qui présente une forte activité antivirale contre de nombreux virus à ARN. Il sert de substrat alternatif et de terminateur de chaîne d'ARN pour l'ARN polymérase virale dépendante de l'ARN. La concentration non toxique de GS-441524 dans les cellules félines est aussi élevée que 100, ce qui inhibe efficacement la réplication du FIPV dans la culture cellulaire CRFK et les macrophages péritonéaux de chat naturellement infectés avec une concentration aussi faible que 1.
Q : Qu'est-ce que GS ?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Il est actuellement disponible sous forme d'injection ou de médicament oral, bien que la version orale ne soit pas encore largement disponible. Veuillez demander à un administrateur !
Q : Combien de temps dure le traitement ?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
Q : Comment puis-je administrer les injections de GS ?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
Emballage:
- par sac ou boîte en carton
PS : nous acceptons la personnalisation de l'emballage.
Expédition:
Nous expédions des marchandises via DHL, Fedex, UPS, TNT, China Post, NL Post et d'autres courriers, d'un poids de 10g à 1000kg ou même en vrac.
Shipping details & shipping documents will be provided and sent to customers as long as it is ready.
Nous continuons à suivre l'expédition jusqu'à ce que les clients soient bien reçus.
After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safety and efficiently.
1kg/foil bag, 25kg/bag or drum (PV bag for inner packing, and aluminium foil bag for outer packing.)
20 tons/20ft container,
25 tons/40ft container,
Or follow the client's requirements.
Delivery : We have special line transportation, or we can give it to yourforwarder Our special line transport is to ensure safe delivery to yourdesignated location, can be free of customs clearance (FedEx /EMS UPSDHL/TNT)
Payment: t/t, paypal, alibaba trade assurance,western union,bitcoin...Allmeans are acceptable as long as they are convenient for you(We do not acceptL/C and D/P during coronavirus)
Package:To better ensure thesafety of your goods, professionalenvironmentally friendly, convenient and efficient packaging services will beprovided.(1kg/25kgs/160kgs/200kgs)
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In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
1.High quality with competitive price.
2.All purity>99%.
3.We are manufacturer and can provide high quality products with factory price.
PRE-SALES
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2.visit factory We can show you around our production plant
3.sample service You can get a sample of the product you want to buy
AFTER-SALES
1.safety delivery If there is any problem in transit, our company willmake up for it
2.quality assurance We can provide you with the test report of theproduct
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Good after-sales service
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