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Nome do produto |
Gs441524 |
Aparición |
White powder,pill,liquid type |
Ensaio |
>99% |
Proba |
HPLC |
CAS |
1191237-69-0 |
MF |
C12H13N5O4 |
Temperatura de almacenamento |
Lugar fresco e seco |
Introdución
GS-441524 é o compoñente bioloxicamente activo de Remdesivir e foi amplamente utilizado en todo o mundo para curar de forma segura e eficaz os gatos da peritonite infecciosa felina (FlP) durante máis de 18 meses. A FIP é unha enfermidade común e altamente mortal dos gatos.
Función
GS-441524 é unha pequena molécula cun nome científico de inhibidor competitivo do nucleósido trifosfato, que mostra unha forte actividade antiviral contra moitos virus de ARN. Serve como substrato alternativo e terminador da cadea de ARN para a ARN polimerase dependente do ARN viral. A concentración non tóxica de GS-441524 en células felinas é de ata 100, o que inhibe efectivamente a replicación de FIPV en cultivos de células CRFK e macrófagos peritoneais de gatos infectados de forma natural cunha concentración tan baixa como 1.
P: Que é GS?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Actualmente está dispoñible como unha inxección ou un medicamento oral aínda que a versión oral aínda non está amplamente dispoñible. Pregúntalle a un administrador!
P: Canto dura o tratamento?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
P: Como podo dar as inxeccións de GS?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
Embalaxe:
- por bolsa ou caixa de cartón
PD: aceptamos a personalización do envase.
Envío:
Enviamos mercadorías a través de DHL, Fedex, UPS, TNT, China Post, NL Post e outros correos, con un peso de 10 g a 1000 kg ou incluso a granel.
Shipping details & shipping documents will be provided and sent to customers as long as it is ready.
Seguimos rastrexando o envío ata que os clientes sexan ben recibidos.
After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safety and efficiently.
1kg/foil bag, 25kg/bag or drum (PV bag for inner packing, and aluminium foil bag for outer packing.)
20 tons/20ft container,
25 tons/40ft container,
Or follow the client's requirements.
Delivery : We have special line transportation, or we can give it to yourforwarder Our special line transport is to ensure safe delivery to yourdesignated location, can be free of customs clearance (FedEx /EMS UPSDHL/TNT)
Payment: t/t, paypal, alibaba trade assurance,western union,bitcoin...Allmeans are acceptable as long as they are convenient for you(We do not acceptL/C and D/P during coronavirus)
Package:To better ensure thesafety of your goods, professionalenvironmentally friendly, convenient and efficient packaging services will beprovided.(1kg/25kgs/160kgs/200kgs)
Hebei Weimiao Import and Export Trade Co., Ltd.is specialized inR&D, manufacturingand marketing APIS,pharmaceuticalintermediates, we have two affiliated manufacturers. More than 70percent products are exported to Europe,America, Japan and Southeast Asia.Our factory located in Hebei, a beautiful coastal cityin the east region of China.
In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
1.High quality with competitive price.
2.All purity>99%.
3.We are manufacturer and can provide high quality products with factory price.
PRE-SALES
1.reply timely We supply from stock and can deliver the goods to youin time
2.visit factory We can show you around our production plant
3.sample service You can get a sample of the product you want to buy
AFTER-SALES
1.safety delivery If there is any problem in transit, our company willmake up for it
2.quality assurance We can provide you with the test report of theproduct
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Good after-sales service
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