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Номи маҳсулот |
Gs441524 |
Намуди зоҳирӣ |
White powder,pill,liquid type |
Таҳлил |
>99% |
Санҷиш |
HPLC |
CAS |
1191237-69-0 |
МФ |
C12H13N5O4 |
Ҳарорати нигоҳдорӣ |
Ҷои хушк |
Муқаддима
GS-441524 ҷузъи аз ҷиҳати биологии фаъоли Remdesivir аст ва дар тӯли зиёда аз 18 моҳ барои бехатар ва самаранок табобати гурбаҳои перитонити сироятии гурбаҳо (FlP) дар саросари ҷаҳон васеъ истифода мешавад. FIP як бемории маъмул ва хеле марговари гурбаҳо мебошад.
Функсия
GS-441524 як молекулаи хурд бо номи илмии ингибитори рақобатпазири нуклеозидтрифосфат мебошад, ки бар зидди бисёр вирусҳои РНК фаъолияти пурқуввати антивирусиро нишон медиҳад. Он ҳамчун субстрати алтернативӣ ва терминатори занҷири РНК барои полимеразаи аз РНК вобастаи вирусӣ хизмат мекунад. Консентратсияи ғайри токсикии GS-441524 дар ҳуҷайраҳои гурба то 100 зиёд аст, ки ин репликатсияи FIPV-ро дар фарҳанги ҳуҷайраҳои CRFK ва макрофагҳои табиии сироятшудаи гурба бо консентратсияи то 1 паст мекунад.
Савол: GS чист?
A: GS is short for GS-441524 which is an experimental anti-viral drug (nucleoside analog) that has cured cats with FIP in field trials conducted at UC Davis but Dr. Neils Pedersen and his team. See study here.
Дар айни замон он ҳамчун сӯзандору ё доруҳои шифоҳӣ дастрас аст, гарчанде ки версияи даҳонӣ то ҳол ба таври васеъ дастрас нест. Илтимос аз админ пурсед!
Савол: Муолиҷа чанд вақт аст?
A: Recommended treatment based on Dr. Pedersen’s original field trial is a minimum of 12 weeks of daily sub-cutaneous injections.
Bloodwork should be checked at the end of 12 weeks and cat’s symptoms should be assessed to see if additional treatment is needed.
Q: What exactly are “neuro” or “ocular” cases?
A: “Neuro” cat means that FIP has crossed the blood brain barrier and symptoms include central nervous system issues. Ataxia (weakness in my back legs especially), inability to jump fully without hesitation, lack of coordination and seizures may occur. Ocular involvement, which is common with the neurological form since the eyes and brain are closely connected, looks like this:
Савол: Чӣ тавр ман сӯзандоруҳои GS-ро медиҳам?
A: The injections are given sub-cutaneously or “sub-cu” which means just under the skin. Injections are to be given every 24 hours at as close to the same time everyday as is possible for at least 12 weeks. The needle should NOT poke into the muscle of the cat. The GS stings upon injection but the pain is over as soon as the injection is over. There are several helpful videos that our members have posted showing how they inject and also many on YouTube. It’s best to have your vet do the first injection or two and to teach you how to do them. Kitties that are more difficult to restrain for the shots may require daily trips to the vet
Бастабандӣ:
- бо халта ё қуттии картон
PS: Мо мутобиқсозии бастабандиро қабул мекунем.
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Мо пайгирии интиқолро идома медиҳем, то он даме, ки мизоҷон хуб қабул карда шаванд.
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Delivery : We have special line transportation, or we can give it to yourforwarder Our special line transport is to ensure safe delivery to yourdesignated location, can be free of customs clearance (FedEx /EMS UPSDHL/TNT)
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In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
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