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  • GS-441524 nigice cyibinyabuzima gikora Remdesivir

Werurwe. 19, 2023 23:25 Subira kurutonde

GS-441524 nigice cyibinyabuzima gikora Remdesivir



Intangiriro

GS-441524 nigice cyibinyabuzima cya Remdesivir kandi cyakoreshejwe henshi kwisi kugirango gikize neza kandi neza neza injangwe zanduye peritonite yanduye (FlP) mumezi arenga 18. FIP nindwara isanzwe kandi yica cyane injangwe.

Imikorere

GS-441524 ni molekile ntoya ifite izina rya siyanse ya nucleoside triphosphate irwanya inhibitor, yerekana ibikorwa bikomeye bya virusi irwanya virusi nyinshi za RNA. Ikora nk'ubundi buryo bwo guhinduranya hamwe no kurangiza urunigi rwa RNA kuri virusi ya RNA iterwa na RNA polymerase. Ubushuhe butari uburozi bwa GS-441524 mu ngirabuzimafatizo ni 100, ibyo bikaba bibuza kwigana FIPV mu muco w’akagari ka CRFK ndetse na macrophage ya peritoneal yanduye bisanzwe.。 

Ikibazo: GS ni iki?
Igisubizo: GS ni ngufi kuri GS-441524 ikaba ari imiti igerageza kurwanya virusi (analogos nucleoside) yakijije injangwe na FIP mu bigeragezo byakorewe muri UC Davis ariko Dr. Neils Pedersen nitsinda rye. Reba kwiga hano.
Kugeza ubu iraboneka nk'inshinge cyangwa imiti yo mu kanwa nubwo verisiyo yo mu kanwa itaraboneka henshi. Nyamuneka saba umuyobozi!
Ikibazo: Kuvura igihe kingana iki?
Igisubizo: Gusabwa kuvurwa hashingiwe ku igeragezwa ryambere rya Dr. Pedersen ni byibura ibyumweru 12 byo guterwa buri munsi.
Amaraso agomba kugenzurwa nyuma yibyumweru 12 hanyuma ibimenyetso byinjangwe bigomba gusuzumwa kugirango harebwe niba hakenewe ubundi buvuzi.

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