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  • Ko te GS-441524 te waahanga koiora o Remdesivir

Mar. 19, 2023 23:25 Hoki ki te rarangi

Ko te GS-441524 te waahanga koiora o Remdesivir



Kupu Whakataki

Ko te GS-441524 te waahanga koiora o Remdesivir a kua whakamahia whanuitia puta noa i te ao ki te rongoa i nga ngeru o te peritonitis infectious peritonitis (FlP) mo te 18 marama neke atu. Ko te FIP he mate noa, he mate tino mate o nga ngeru.

Mahi

Ko te GS-441524 he ngota ngota iti me te ingoa putaiao o te nucleoside triphosphate aukati whakataetae, e whakaatu ana i nga mahi pareketo kaha ki te maha o nga huaketo RNA. Ka noho hei tïpako rereke me te kaiwhakamutu mekameka RNA mo te RNA polymerase RNA-whakaaro ki te RNA. Ko te kukū kore-paitini o GS-441524 i roto i nga pūtau kuia he 100 te teitei, e aukati ana i te tukuruatanga FIPV i roto i te ahurea pūtau CRFK me nga macrophages peritoneal ngeru kua pangia me te kukū.。 

Q: He aha te GS?
A: He poto te GS mo te GS-441524 he rongoa whakawetiweti whakamatautau (nucleoside analog) i whakaora nga ngeru me te FIP i roto i nga whakamatautau mara i whakahaerehia i UC Davis engari ko Takuta Neils Pedersen me tana roopu. Tirohia te ako i konei.
I tenei wa e waatea ana hei werohanga, hei rongoa-a-waha ranei ahakoa kaore ano kia whanuitia te putanga-a-waha. Tena koa patai ki tetahi kaiwhakahaere!
Q: Kia pehea te roa o te maimoatanga?
A: Ko te maimoatanga e taunakihia ana i runga i te whakamatautau mara tuatahi a Takuta Pedersen ko te iti rawa o nga wiki 12 o nga werohanga i raro i te kiri o ia ra.
Me tirotirohia nga mahi toto i te mutunga o nga wiki 12 me te aromatawai i nga tohu o te ngeru kia kitea mena ka hiahiatia etahi atu maimoatanga.

Tiria
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