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Mar. 19, 2023 23:25 Komawa zuwa lissafi

GS-441524 shine bangaren ilimin halitta mai aiki na Remdesivir



Gabatarwa

GS-441524 shine kayan aikin Remdesivir na ilimin halitta kuma an yi amfani dashi a ko'ina cikin duniya don a amince da maganin kuliyoyi na peritonitis na feline (FlP) sama da watanni 18. FIP cuta ce ta kowa kuma mai saurin kisa na kuliyoyi.

Aiki

GS-441524 karamin kwayoyin halitta ne tare da sunan kimiyya na nucleoside triphosphate competitive inhibitor, wanda ke nuna karfi na antiviral aiki a kan yawancin ƙwayoyin RNA. Yana aiki azaman madadin madaidaicin da sarkar sarkar RNA don RNA polymerase mai dogaro da RNA mai hoto. Matsayin da ba mai guba ba na GS-441524 a cikin ƙwayoyin feline ya kai 100, wanda ke hana kwafin FIPV da kyau a cikin al'adun sel na CRFK da kamuwa da cuta ta dabi'a na macrophages cat peritoneal tare da maida hankali.。 

Tambaya: Menene GS?
A: GS gajere ne ga GS-441524 wanda shine gwajin gwajin gwaji (analog nucleoside) wanda ya warkar da kuliyoyi tare da FIP a cikin gwajin filin da aka gudanar a UC Davis amma Dr. Neils Pedersen da tawagarsa. Dubi karatu a nan.
A halin yanzu ana samunsa azaman allura ko magani na baka duk da cewa nau'in na baka har yanzu ba a samu ko'ina ba tukuna. Da fatan za a tambayi admin!
Tambaya: Yaya tsawon lokacin magani?
A: Magani da aka ba da shawarar dangane da ainihin gwajin filin Dr. Pedersen shine mafi ƙarancin makonni 12 na alluran da ba a kai ga fata ba.
Ya kamata a duba aikin jini a ƙarshen makonni 12 kuma ya kamata a tantance alamun cat don ganin ko ana buƙatar ƙarin magani.

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