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  • GS-441524 ndiyo biologically inoshanda chikamu cheRemdesivir

Mar . 19, 2023 23:25 Back to list

GS-441524 ndiyo biologically inoshanda chikamu cheRemdesivir



Nhanganyaya

GS-441524 ndiyo biologically inoshanda chikamu cheRemdesivir uye yakashandiswa zvakanyanya pasi rese kurapa zvakachengeteka uye nemazvo katsi dzefeline infectious peritonitis (FlP) kweinodarika mwedzi gumi nemasere. FIP chirwere chinowanzoitika uye chinouraya zvikuru chekitsi.

Basa

GS-441524 imorekuru diki rine zita resainzi rekuti nucleoside triphosphate competitive inhibitor, rinotaridza kuita kwakasimba kweantiviral kurwisa mavhairasi mazhinji eRNA. Iyo inoshanda seimwe substrate uye RNA ketani terminator yehutachiona RNA-inotsamira RNA polymerase. Iyo isiri-chepfu yekusangana kweGS-441524 mumaseru efeline yakakwira se100, iyo inonyatso kuvharidzira kudzokororwa kweFIPV muCRFK cell tsika uye inotapukirwa nekatsi peritoneal macrophages ine kusungwa.。 

Mubvunzo: Chii chinonzi GS?
A: GS ipfupi kune GS-441524 inova yekuedza anti-viral drug (nucleoside analog) iyo yakarapa katsi neFIP mumiedzo yemumunda yakaitwa paUC Davis asi Dr. Neils Pedersen neboka rake. Ona kudzidza pano.
Parizvino inowanikwa sejekiseni kana mushonga wemukanwa kunyangwe shanduro yemuromo haisati yave kuwanikwa zvakanyanya. Ndokumbirawo kubvunza admin!
Mubvunzo: Inguva yakareba sei kurapwa?
A: Mishonga inokurudzirwa yakavakirwa pakuedza kwepakutanga kwaDr. Pedersen inguva shoma yemavhiki gumi nemaviri emazuva ese e-sub-cutaneous majekiseni.
Kushanda kweropa kunofanirwa kuongororwa pakupera kwemasvondo gumi nemaviri uye zviratidzo zvekitsi zvinofanirwa kuongororwa kuona kana kumwe kurapwa kuchidiwa.

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