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  • GS-441524 yog cov khoom siv roj ntsha ntawm Remdesivir

Mar. Peb 19, 2023 23:25 Rov qab mus rau npe

GS-441524 yog cov khoom siv roj ntsha ntawm Remdesivir



Taw qhia

GS-441524 yog cov tshuaj lom neeg lom neeg ntawm Remdesivir thiab tau siv dav thoob ntiaj teb kom muaj kev nyab xeeb thiab zoo kho miv ntawm feline kis kab mob peritonitis (FlP) rau ntau tshaj 18 lub hlis. FIP yog ib yam kab mob uas tshwm sim thiab tuag taus ntawm miv.

Muaj nuj nqi

GS-441524 yog ib qho me me molecule nrog lub npe tshawb fawb ntawm nucleoside triphosphate kev sib tw inhibitor, uas qhia tau hais tias muaj zog tiv thaiv kab mob tiv thaiv ntau tus kab mob RNA. Nws ua hauj lwm ua lwm yam substrate thiab RNA saw terminator rau kab mob RNA-dependent RNA polymerase. Qhov tsis muaj tshuaj lom neeg concentration ntawm GS-441524 nyob rau hauv feline hlwb yog siab li 100, uas zoo inhibits FIPV replication nyob rau hauv CRFK cell kab lis kev cai thiab lawm kab mob miv peritoneal macrophages nrog ib tug concentration.。 

Q: GS yog dab tsi?
A: GS luv luv rau GS-441524 uas yog ib qho kev sim tshuaj tiv thaiv kab mob (nucleoside analog) uas tau kho cov miv nrog FIP hauv kev sim ua haujlwm ntawm UC Davis tab sis Dr. Neils Pedersen thiab nws pab neeg. Saib kev kawm ntawm no.
Nws yog tam sim no muaj nyob rau hauv kev txhaj tshuaj lossis tshuaj noj hauv qhov ncauj txawm hais tias qhov ncauj version tseem tsis tau muaj dav. Thov nug tus admin!
Q: Kev kho mob ntev npaum li cas?
A: Pom zoo kho raws li Dr. Pedersen qhov kev sim thawj zaug yog qhov tsawg kawg ntawm 12 lub lis piam ntawm kev txhaj tshuaj subcutaneous txhua hnub.
Cov ntshav yuav tsum tau kuaj xyuas thaum kawg ntawm 12 lub lis piam thiab miv cov tsos mob yuav tsum tau soj ntsuam xyuas seb puas xav tau kev kho mob ntxiv.

Qhia
Tom ntej:

Xov xwm tshiab

Yog tias koj txaus siab rau peb cov khoom, koj tuaj yeem xaiv tawm koj cov ntaub ntawv ntawm no, thiab peb yuav tiv tauj koj sai sai.


Ntaus nkag mus tshawb lossis ESC kom kaw
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