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Mati. 19, 2023 23:25 Toe fo'i i le lisi

GS-441524 o le vaega faʻaola ola ole Remdesivir



Folasaga

O le GS-441524 o le vaega olaola o le Remdesivir ma ua fa'aaogaina lautele i le lalolagi atoa e fofo ai ma le saogalemu ma lelei pusi o feline infectious peritonitis (FlP) mo le silia ma le 18 masina. O le FIP ose fa'ama'i taatele ma sili ona oti o pusi.

Galuega

GS-441524 o se tamai mole ma se igoa faasaienisi o le nucleoside triphosphate inhibitor tauvaga, lea e faʻaalia ai le malosi o le antiviral e faasaga i le tele o siama RNA. E fai ma sui sui ma RNA filifili terminator mo viral RNA-faalagolago RNA polymerase. Ole maualuga ole GS-441524 ile feline cell e maualuga ile 100, lea e taofia lelei ai le toe faia o le FIPV ile CRFK cell culture ma faʻamaʻi faʻanatura pusi peritoneal macrophages ma se faʻatonuga.。 

Q: O le a le GS?
A: GS e puupuu mo le GS-441524 o se faʻataʻitaʻiga anti-viral vailaʻau (nucleoside analog) na faʻamalolo pusi ma FIP i faʻataʻitaʻiga faʻataʻitaʻiga na faia i UC Davis ae Dr. Neils Pedersen ma lana 'au. Va'ai su'esu'ega iinei.
O lo'o maua i le taimi nei o se tui po'o se vaila'au tu'u gutu e ui lava e le'o maua lautele le fa'amatalaga tu'u. Fa'amolemole fesili i se admin!
Q: O le a le umi ole togafitiga?
A: Fautuaina togafitiga fa'avae ile su'esu'ega muamua a Dr. Pedersen ole la'ititi ole 12 vaiaso ole tui ile pa'u ile aso.
E tatau ona siaki le toto ile fa'ai'uga o le 12 vaiaso ma e tatau ona su'esu'e fa'ailoga o pusi e iloa ai pe mana'omia ni togafitiga fa'aopoopo.

Faasoa
Sosoo:

Tala fou

Afai e te fiafia i a matou oloa, e mafai ona e filifili e tuʻu lau faʻamatalaga iinei, ma o le a matou fesoʻotaʻi ma oe i se taimi lata mai.


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