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  • What is GHRP-2?

    What is GHRP-2?

    Essentially it is a synthetic version of ghrelin analogue.GHRP-2 stimulates the release of an endogenous growth hormone (GH) within the somatotrophs of the anterior pituitary in the animal and human body.Specifically, it will increase the number of somatotrophs in a GH pulse by limiting the amount of somatostatin present.Standard GHRH increases the amplitude at which the pituitary cells pulse.
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  • TYPES OF GHRPS

    TYPES OF GHRPS

    This type of GHRP stimulates the production of less HGH than the others. It has been found to enhance GH plasma growth in humans and animals. However, the medically documented effectiveness of Ipamorelin has not been satisfactorily demonstrated because clinical trials investigating its performance were never completed. It is perhaps the mildest of GHRPs we offer, however it is also very well tolerated and blood work analysis indicates a level of effectiveness that cannot be ignored. Ipamorelin signals a strong, stable GH pulse that closely mimics natural GH production, and it does so without the often undesirable side-effect of increased appetite.
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  • DIFFERENCE BETWEEN GHRP 2 AND GHRP 6

    DIFFERENCE BETWEEN GHRP 2 AND GHRP 6

    One of the major differences between GHRP 2 and GHRP 6 is that the latter increases hunger in you substantially, especially when the subject of study consume the supplement at regular intervals. Therefore, those looking to build muscles and lose excess fat may want to consider GHRP 2 as it is not known to build appetite in subjects of study to that extent. However, if the study aim is to eat more and growth quickly than GHRP 6 is better.
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  • What is GW 0742

    What is GW 0742

    GW0742 is a recently famed drug, often mentioned in comparison with Cardarine. This drug is mostly used by athletes to improve their stamina. The fat affecting properties of GW0742 also make it a good promoter of energy in the body. Additionally, this drug helps increase the oxidative abilities of your body muscles.PPARδ/β agonist, GW0742, has been investigated for its usage as a drug by GlaxoSmithKline. Its atomic structure reveals just one minor difference between GW0742 and Cardarine. Yet, this drug takes the lead over Cardarine. Many people claim that GW0742 is around 200 times more effective than Cardarine.The uses and mode of action for GW0742 are almost similar to those of Cardarine. However, this drug is more powerful and has many additional benefits too. Several studies to discover other possible uses of GW0742 are currently underway. It is expected that more information about this drug will be revealed soon.
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  • Pulmonary Administration of GW0742

    Pulmonary Administration of GW0742

    Pulmonary emphysema is a disease in which lung alveoli are irreversibly damaged, thus compromising lung function. Our previous study revealed that all-trans-retinoic acid (ATRA) induces the differentiation of human lung alveolar epithelial type 2 progenitor cells and repairs the alveoli of emphysema model mice. ATRA also reportedly has the ability to activate peroxisome proliferator-activated receptor (PPAR) beta/delta. A selective PPARbeta/delta ligand has been reported to induce the differentiation of human keratinocytes during wound repair. Here, we demonstrate that treatment using a high-affinity PPARbeta/delta agonist, GW0742, reverses the lung tissue damage induced by elastase in emphysema-model mice and improves respiratory function. Mice treated with elastase, which collapsed their alveoli, were then treated with either 10% dimethyl sulfoxide (DMSO) in saline (control group) or GW0742 (1.0 mg/kg twice a week) by pulmonary administration. Treatment with GW0742 for 2 weeks increased the in vivo expression of surfactant proteins A and D, which are known alveolar type II epithelial cell markers. GW0742 treatment also shortened the average distance between alveolar walls in the lungs of emphysema model mice, compared with a control group treated with 10% DMSO in saline. Treatment with GW0742 for 3 weeks also improved tissue elastance (cm H2O/mL), as well as the ratio of the forced expiratory volume in the fi rst 0.05 s to the forced vital capacity (FEV 0.05/FVC). In each of these experiments, GW0742 treatment reversed the damage caused by elastase. In conclusion, PPARbeta/delta agonists are potential therapeutic agents for pulmonary emphysema.
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  • What is semaglutide？

    What is semaglutide？

    Semaglutide belongs to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs. It mimics the GLP-1 hormone, released in the gut in response to eating. One role of GLP-1 is to prompt the body to produce more insulin,  which reduces blood sugar (glucose). For that reason, health care providers have used semaglutide for more than 15 years to treat Type 2 diabetes. But GLP-1 in higher amounts also interacts with the parts of the brain that suppress your appetite and signal you to feel full. When used in conjunction with diet and exercise, it can cause significant weight loss — and a reduced risk of cancer,diabetes and heart disease — in people who are obese or overweight.
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  • Semaglutide market report in 2023

    Semaglutide market report in 2023

    Semaglutide (CAS No:  910463-68-2), belongs to GLP-1 RAs(glucagon-like peptide-1 receptor agonists), is an antidiabetic medication used for the treatment of type 2 diabetes and an anti-obesity medication used for long-term weight management, developed by Novo Nordisk in 2012. The compound patent of will be expiried in 2026.  Semaglutide is quite popular and has a very promising market demand due to its excellent function (for treating diabetes and losing weight) with no obvious side-effect and advanced technology.
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  • 910463-68-2 Usage

    910463-68-2 Usage

    Semaglutide, sold under the brand name Ozempic among others, is an anti-diabetic medication used for the treatment of type 2 diabetes and chronic weight management. Semaglutide acts like human glucagon-like peptide-1 (GLP-1) such that it increases insulin secretion, thereby increasing sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action, thus, only once-a-week injection is sufficient.
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  • Medications Containing Semaglutide Marketed for Type 2 Diabetes or Weight LossWhat is semaglutide?

    Medications Containing Semaglutide Marketed for Type 2 Diabetes or Weight LossWhat is semaglutide?

    Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. It mimics the GLP-1 hormone that is released in the gastrointestinal tract in response to eating. One role of GLP-1 is to prompt the body to produce more insulin, which reduces blood glucose (sugar). GLP-1 in higher amounts also interacts with the parts of the brain that reduce appetite and signal a feeling of fullness.There are currently three FDA-approved semaglutide products:Ozempic injection and Rybelsus tablets are approved to lower blood sugar levels in adults with type 2 diabetes mellitus, in addition to diet and exercise. Ozempic is also approved to reduce the risk of heart attack, stroke, or death in adults with type 2 diabetes mellitus and known heart disease.
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