
Semaglutide, a groundbreaking pharmaceutical intermediate, has redefined the treatment landscape for type 2 diabetes and obesity. This synthetic peptide, chemically engineered to mimic the natural hormone glucagon-like peptide-1 (GLP-1), offers a unique combination of efficacy and convenience. As a active pharmaceutical intermediate, Semaglutide is designed to enhance glycemic control and support weight management through its prolonged action and targeted mechanism.
Semaglutide's molecular structure is a testament to modern pharmaceutical innovation. With a chemical formula of C187H291N45O59 and a formula weight of 4113.57754 g/mol, it is engineered for stability and bioavailability. Its high purity (>98%) ensures consistent therapeutic outcomes. The powder form allows for precise dosing and flexibility in formulation, making it a preferred choice for researchers and manufacturers.
One of Semaglutide's standout features is its extended half-life of approximately 7 days in humans. This is achieved through structural modifications, including the substitution of Gly with 2-aminoisobutyric acid (Aib) and the addition of an 18-carbon fatty acid moiety. These enhancements increase its resistance to degradation and improve binding affinity to serum albumin, reducing the need for frequent administration. This makes it an ideal candidate for pharmaceutical intermediates in long-acting formulations.
| Parameter | Details |
|---|---|
| CAS No. | 910463-68-2 |
| Chemical Name | Semaglutide |
| Synonyms | Sermaglutide, Semaglutide fandachem, Semaglutide impurity, etc. |
| Molecular Formula | C187H291N45O59 |
| Formula Weight | 4113.57754 g/mol |
| Appearance | White to off-white solid powder |
| Purity | >98% |
| Storage | Dry, dark, 0-4°C (short-term) or -20°C (long-term) |
| Solubility | Soluble in DMSO |
| Shipping Condition | Ambient temperature, non-hazardous |
Semaglutide's versatility extends beyond its primary role in diabetes care. As a pharmaceutical intermediate, it is widely used in the development of treatments for obesity, with clinical trials demonstrating its efficacy in weight loss. Researchers are also exploring its potential in neurodegenerative diseases like Alzheimer's, where GLP-1 receptor agonists show promise in protecting neuronal function.
The peptide's ability to enhance insulin secretion and suppress glucagon release makes it a cornerstone in managing type 2 diabetes. Its anti-diabetic properties are further amplified by its appetite-suppressing effects, offering a dual benefit for patients with comorbid obesity.
As a leading manufacturer of active pharmaceutical intermediates, Hebei Weimiao has established itself as a trusted supplier in the global pharmaceutical industry. The company's commitment to quality is reflected in its rigorous testing protocols and adherence to international standards.

Hebei Weimiao's state-of-the-art facilities ensure the production of Semaglutide with pharmaceutical-grade purity. The company's comprehensive quality control measures include third-party testing, ensuring compliance with regulatory requirements. This dedication to excellence has earned the trust of clients worldwide.
Hebei Weimiao's competitive edge lies in its ability to offer flexible solutions tailored to client needs. Whether you require buy pharmaceutical intermediates in small quantities for research or large-scale production, the company's pharmaceutical intermediates market presence ensures reliable supply chains.

The company's logistics network guarantees safe and timely delivery, with options for payment including Bitcoin, Western Union, T/T, and more. Hebei Weimiao's transparent policies and customer-centric approach make it an ideal partner for pharmaceutical manufacturers and researchers.
Q: Are you a trading company or manufacturer?
A: We are a manufacturer, ensuring direct control over product quality and specifications.
Q: Do you provide samples?
A: Yes, samples are available for evaluation before bulk production.
Q: What are your payment terms?
A: We accept Western Union, T/T, BTC, and other secure payment methods.
Q: How do you ensure product quality?
A: Our products undergo 100% testing before delivery, with third-party verification available upon request.
The development and application of Semaglutide align with the rigorous standards upheld by the National Institute of Standards and Technology (NIST). As a leader in measurement science, NIST's work in standardizing pharmaceutical processes ensures the accuracy and reliability of compounds like Semaglutide. According to NIST, "Precise measurements are critical for the development of safe and effective medical treatments" (NIST.gov).
Semaglutide represents a significant advancement in the treatment of diabetes and obesity, with its unique pharmacological profile and versatility in application. Hebei Weimiao Import and Export Trade Co., Ltd. stands out as a reliable supplier of pharmaceutical intermediates, combining cutting-edge technology with a commitment to quality. Whether you are a researcher, manufacturer, or healthcare provider, partnering with Hebei Weimiao ensures access to premium-grade Semaglutide tailored to your needs.

For more information, visit Hebei Weimiao's product page or contact their team for customized solutions. With a focus on innovation and excellence, Hebei Weimiao continues to drive progress in the pharmaceutical industry.