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Product Description
Semaglutide CAS No. 910463-68-2
Semaglutide has a chemical structure that is very similar to the hormone glucagon-like peptide 1 (GLP-1), adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.
Semaglutide may help people with obesity lose weight as well.
CAS NO: |
910463-68-2 |
Product Name: |
Semaglutide |
Synonyms: |
Sermaglutide;Semaglutide fandachem;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2 |
Molecular Formula: |
C187H291N45O59 |
Formula Weight: |
4113.57754 |
Appearance: |
Solid powder |
Purity: |
>98% |
Storage: |
Dry, dark, and at 0 - 4 C for the short term (days to weeks) or -20 C for the long term (months to years). |
Solubility: |
Soluble in DMSO |
Shipping Condition: |
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Function
Semaglutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans
Application
Weight loss
Anti-diabetes
Alzheimer's disease
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Hebei Weimiao Import and Export Trade Co., Ltd.is specialized inR&D, manufacturingand marketing APIS,pharmaceuticalintermediates, we have two affiliated manufacturers. More than 70percent products are exported to Europe,America, Japan and Southeast Asia.Our factory located in Hebei, a beautiful coastal cityin the east region of China.
In the pastt years,Hebei Weimiao Import and Export Trade Co., Ltd.has established its professional team and advanced managements.excels in product sourcing and customized products. Development ofnew fine chemical, custom synthesis has been a significant part ofour chemical's production.
With our policy:"Credibility, Quality and Customer First".Wesincerely wish to tightly cooperate with the clients who areinterested in our products.
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