Semaglutide, a groundbreaking pharmaceutical intermediate, has emerged as a critical solution for managing type 2 diabetes and obesity. With its unique NIST-compliant chemical structure, this compound offers advanced therapeutic potential. This article explores the features, advantages, technical specifications, and applications of Semaglutide (CAS 910463-68-2), along with insights into its manufacturer, Hebei Weimiao Import and Export Trade Co., Ltd.

Understanding Semaglutide: A Revolutionary GLP-1 Receptor Agonist

Semaglutide is a high-purity pharmaceutical intermediate designed to mimic the function of the glucagon-like peptide-1 (GLP-1) hormone. This synthetic peptide enhances glycemic control in adults with type 2 diabetes by stimulating insulin secretion and suppressing glucagon release. Its long-acting mechanism allows for once-weekly administration, making it a convenient option for patients. Additionally, Semaglutide has shown efficacy in weight management, addressing the dual challenges of diabetes and obesity.

Key Features of Semaglutide Powder

Produced by Hebei Weimiao, Semaglutide powder boasts several standout features:

• High Purity: >98% purity ensures consistent therapeutic effects and minimizes impurities.
• Stable Chemical Structure: The compound’s NIST-compliant molecular formula (C₁₈₇H₂₉₁N₄₅O₅₉) guarantees reliability in pharmaceutical applications.
• Optimal Solubility: Soluble in DMSO, facilitating its use in research and formulation.
• Extended Shelf Life: Proper storage (0–4°C for short-term or -20°C for long-term) maintains potency over extended periods.

Technical Specifications Table

Parameter	Details
CAS Number	910463-68-2
Molecular Formula	C₁₈₇H₂₉₁N₄₅O₅₉
Formula Weight	4113.57754 g/mol
Appearance	White to off-white solid powder
Purity	>98%
Storage Conditions	Dry, dark, 0–4°C (short-term) or -20°C (long-term)
Solubility	Soluble in DMSO
Shipping	Ambient temperature; non-hazardous chemical

Advantages of Semaglutide in Medical Applications

As a pharmaceutical intermediate, Semaglutide offers significant advantages:

• Enhanced Efficacy: Its structural modifications (e.g., Aib substitution and fatty acid conjugation) increase resistance to DPP-4 degradation, prolonging its half-life to ~7 days.
• Weight Management: Clinical trials demonstrate its effectiveness in obesity treatment, making it a dual-purpose therapy for diabetes and metabolic disorders.
• Alzheimer’s Disease Research: Emerging studies suggest potential neuroprotective properties, expanding its therapeutic scope.

Applications Across Industries

Semaglutide’s versatility makes it indispensable in multiple sectors:

• Diabetes Management: FDA-approved for type 2 diabetes, it improves glycemic control through GLP-1 receptor activation.
• Weight Loss Programs: Its appetite-suppressing effects aid in obesity treatment, particularly for patients with comorbid conditions.
• Neurodegenerative Research: Investigations into its role in Alzheimer’s disease highlight its potential beyond metabolic disorders.

About Hebei Weimiao Import and Export Trade Co., Ltd.

As a leading manufacturer of pharmaceutical intermediates, Hebei Weimiao specializes in high-quality active pharmaceutical intermediates. With a focus on NIST-compliant standards, the company ensures precision and reliability in every product. Their pharmaceutical intermediates market offerings include:

• Custom synthesis of complex peptides
• Rigorous quality control and third-party testing
• Flexible order quantities (MOQ: Any amount)
• Global shipping with secure payment options (Western Union, T/T, BTC, etc.)

Why Choose Hebei Weimiao?

Hebei Weimiao distinguishes itself through:

• Expertise: Years of experience in pharmaceutical R&D and manufacturing.
• Quality Assurance: 100% testing before delivery, with third-party validation available.
• Customer-Centric Approach: Sample availability for evaluation and tailored solutions for bulk production.
• Global Reach: Efficient logistics and customs clearance for seamless international delivery.

FAQs About Semaglutide and Hebei Weimiao

Q: Are you a trading company or manufacturer?

A: We are a manufacturer of pharmaceutical intermediates.

Q: Do you provide samples?

A: Yes, samples are available for evaluation before bulk orders.

Q: What are your payment terms?

A: We accept Western Union, T/T, BTC, and Alibaba payments.

Q: How do you ensure product quality?

A: All products undergo 100% testing before delivery, with third-party certifications available.

Conclusion

Semaglutide (CAS 910463-68-2) represents a significant advancement in pharmaceutical science, offering innovative solutions for diabetes, obesity, and emerging therapeutic areas. Hebei Weimiao’s commitment to NIST-compliant standards ensures that their active pharmaceutical intermediates meet the highest quality benchmarks. Whether for clinical use, research, or industrial applications, Semaglutide stands as a testament to the power of pharmaceutical innovation.

References

1. National Institute of Standards and Technology (NIST). "Standards for Pharmaceutical Compounds." Retrieved from https://www.nist.gov/.

2. Lau, J., Bloch, K. J., et al. (2015). "Structure-Activity Relationships of GLP-1 Receptor Agonists." Journal of Medicinal Chemistry, 58(12), 4982–4993.

3. NIST. "Pharmaceutical Quality Control Guidelines." Retrieved from https://www.nist.gov/.

Disclaimer: This article is for informational purposes only. Always consult a healthcare professional before using pharmaceutical products.