Semaglutide (CAS No: 910463-68-2), belongs to GLP-1 RAs(glucagon-like peptide-1 receptor agonists), is an antidiabetic medication used for the treatment of type 2 diabetes and an anti-obesity medication used for long-term weight management, developed by Novo Nordisk in 2012. The compound patent of will be expiried in 2026.
Semaglutide is quite popular and has a very promising market demand due to its excellent function (for treating diabetes and losing weight) with no obvious side-effect and advanced technology.
*Advanced Production Technique:
With strong technique support, our Sinoway can provide semaglutide produced both by Recombinant protease(biological method,similar to originator) and by peptide synthesis method,together with key intermediates for R&D purpose with no patent infringement area.
*Certification and Document:
Medicine Production License,GMP,DMF,
Highlights:
1. High quality:
*Quality produced by biochemical method:Content: 85.0%~102.0%(on the dried basis)Biological activity 70%~130%.
*Quality produced by polypeptide synthesis:Assay 95.0%~105.0%,S,impurity NMT 0.1%(For more details, pls refer to COAs)
Production under GMP and ICH guideline.
2. Competitive price: much lower than the originator.
3. Key intermediates available in each step with high quality and much lower price.
Steps
Product name(Sequence)+CAS No.
Production method
Quality
Main chain
CAS No.:1169630-82-3
Recombinant protease
Assay 99.0%up
D-enantiomeric purity0.15%below
Side chain 1
tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu
CAS No.:1118767-16-0
Peptide Synthesis
Purity 99.0%up
Side chain 2
Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH
CAS No.:1662688-20-1
Peptide Synthesis
Purity 99.0%up
4. Big capacity :50kg up per month
5. Professional cold chain transportation below 20°C
6. We also provide other semaglutide intermediates with much competitiveness as below:
Octadecanedioic acid CAS:871-70-5
[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid CAS:166108-71-0
Fmoc-His-Aib-OH TFA CAS:1446013-08-6
Boc-L-His(Trt)-Aib-OH , CAS: 2061897-68-3
Ste-Glu-AEEA-AEEA-OSU,CAS:1169630-40-3