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Sourcing of active pharmaceutical ingredients
Considerations when sourcing active pharmaceutical ingredients (APIs) can often be condensed to ones of economy and purity. Here, Dave Elder highlights the importance of defining those attributes that impact final product quality to ensure pharma companies find the best ingredient suppliers.ادامه مطلب -
About active and inactive medicine ingredients
Active ingredients are the chemical compounds in medicines that have an effect on the body. Essentially, they are the ingredients within your medicine that make the medicine work. A ‘brand name’ is the name given to a medicine by the company that makes it. There are many medicines that have the same active ingredients, but are made by different companies and have different brand names.Prescribing and dispensing medicines by their active ingredient(s) means these ingredients are easier to identify on prescriptions and medicine labels.ادامه مطلب -
What is an Active Pharmaceutical Ingredient?
Any substance or combination of substances used in a finished pharmaceutical product (FPP), intended to furnish pharmacological activity or to otherwise have direct effect in the diagnosis, cure, mitigation, treatment or prevention of disease, or to have direct effect in restoring, correcting or modifying physiological functions in human beings.”This definition implies, for example, that commercially available premixes of APIs (such as the popular amoxicillin + clavulanic acid premix) can be regarded as an API, which is not correct. This definition thus may lead to misinterpretation.ادامه مطلب -
Active Pharmaceutical Ingredient: A Brief Overview
An Active Pharmaceutical Ingredient or API is a chemical compound that is an active component in medicine, pesticide, or biological drug. This ingredient can also be called an “active ingredient” or “bulk active” and can be used in natural products.Simply put, it refers to the components of medicine that lead to the desired outcomes. Paracetamol, for instance, has paracetamol as its API.Apart from the active pharmaceutical ingredient definition, this article will help you to understand how APIs are used to make medicine. You shall also explore which significant steps were taken by the government to facilitate and promote the production of these medicines within India to reduce dependency on foreign nations.ادامه مطلب -
Testing of Active Pharmaceutical Ingredients (APIs)
Testing of active pharmaceutical ingredients (APIs) is a routine activity in many Official Medicines Control Laboratories (OMCLs) of the General European OMCL Network (GEON). API testing increases the scope of control, as one source of API can be used in several batches of drug products. In addition, the sensitivity of the method and the ability to determine characteristic impurities at a lower level increase. The sensitivity of the method can be significantly decreased when the method is transferred from API to drug products due to matrix effects.OMCLs also make important contributions to the development and improvement of European Pharmacopoeia (Ph. Eur.) monographs through their active participation in different Ph. Eur. working groups at the EDQM.ادامه مطلب -
What are Active Pharmaceutical Ingredients (APIs)?
APIs are the active components in a pharmaceutical drug that produces the required effect on the body to treat a condition.APIs are produced by processing chemical compounds.In a biologic drug, the active ingredient is known as a bulk process intermediate (BPI).In the context of drug development and manufacturing, APIs are the key active components that interact with specific receptors or target molecules in the body to bring about the desired physiological or therapeutic response.ادامه مطلب -
![Active Pharmaceutical Ingredients [API]](https://www.weimiaobio.com/images/7_202404261221099452.jpg "Active Pharmaceutical Ingredients [API]")
Active Pharmaceutical Ingredients [API]
Active Pharmaceutical Ingredient or API is the biologically active part of the drug present in different types of medications like tablets, capsules, injectables, creams, etc. In simple words, it refers to those ingredients of a drug that produce the intended results. As active pharmaceutical ingredients are very powerful, a small quantity does the job.The name and quantity of an API in medication are mentioned on the over-the-counter drug's package. In some cases, the name of the medicine is the active pharmaceutical ingredient used in it. For example, the API of Paracetamol is paracetamol.ادامه مطلب -
What are API active pharmaceutical ingredients?
The industries that deal with active pharmaceutical ingredients and their pharmaceutical applications must be aware of the new regulations regarding this type of components and substances, especially those that appear in the BOE (Official State Gazette). That is why at DC Fine Chemicals we always try to stay tuned to any updates. In several articles we have mentioned pharmaceutical APIs, but what are they? Throughout this article, as manufacturers of fine chemicals in Spain and the UK, we will talk about this type of substance and we will look at what aspects give it so much importance in modern medicine. But first, bear in mind that you can browse our extensive catalogue of chemical products and get your hands on the ones you need.ادامه مطلب -
![Active Pharmaceutical Ingredients [APIs] and what they mean in the World of Pharma](https://www.weimiaobio.com/images/7_202404261214325452.jpg "Active Pharmaceutical Ingredients [APIs] and what they mean in the World of Pharma")
Active Pharmaceutical Ingredients [APIs] and what they mean in the World of Pharma
Only a small amount of the active ingredient has an effect, so only a tiny part of the active ingredient is contained in the medicine. You will always find the name and amount of the active ingredient contained in the medicine on the package of the drugs that you would purchase from your chemist across the counter.Usually, the manufacturing and production of APIs has traditionally always been carried out by the pharmaceutical companies themselves in their home countries. But in recent years many corporations have opted to send manufacturing overseas to cut costs and spread diversification as well. This has caused significant changes to how API drugs are regulated, with more rigorous guidelines and inspections put into place.ادامه مطلب