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11 月 . 12, 2024 02:43 Back to list

tosyl chloride cas 98-59-9 supplier



Tosyl Chloride (CAS 98-59-9) An Overview and Supplier Insights


Tosyl chloride, also known as p-toluenesulfonyl chloride, is a versatile chemical compound characterized by its sulfonyl chloride functional group. With the chemical formula C7H7ClO2S and a CAS number of 98-59-9, tosyl chloride plays a pivotal role in organic chemistry and various industrial applications. This article delves into the properties, applications, and sourcing considerations for tosyl chloride, providing valuable insights for researchers and manufacturers alike.


Properties of Tosyl Chloride


Tosyl chloride is a colorless to light yellow liquid with a pungent odor. It has a boiling point of approximately 156 °C and a density of around 1.2 g/cm³. As a sulfonyl chloride, it is highly reactive, particularly with nucleophiles. This property makes it a valuable reagent in organic synthesis, enabling the formation of various sulfonyl derivatives.


In terms of solubility, tosyl chloride is soluble in organic solvents such as dichloromethane, benzene, and ether, but it is not soluble in water. When handling this compound, it is crucial to observe safety precautions, as it can cause skin irritation and releases toxic fumes upon contact with moisture.


Applications of Tosyl Chloride


Tosyl chloride serves multiple purposes across different fields. Its primary applications include


1. Protection of Functional Groups In organic synthesis, tosyl chloride is commonly used to protect alcohols and amines. The formation of tosylate esters shields these functional groups during subsequent chemical reactions, allowing for more selective transformations.


2. Reagent in Synthesis Tosyl chloride is utilized as a reagent to convert alcohols into better leaving groups, facilitating nucleophilic substitution reactions. It is particularly valuable in the synthesis of various pharmaceuticals and agrochemicals.


3. Preparation of Sulfonamides Tosyl chloride is instrumental in the synthesis of sulfonamides, which are essential in the pharmaceutical industry for developing antimicrobial agents.


tosyl chloride cas 98-59-9 supplier

tosyl chloride cas 98-59-9 supplier

4. Production of Polymers In polymer chemistry, tosyl chloride is employed in the preparation of tosylate polymers, which can exhibit desirable properties in various applications.


Sourcing Tosyl Chloride


When looking for tosyl chloride suppliers, it is essential to consider several factors to ensure a reliable and high-quality product


1. Reputation and Quality Choose suppliers with a strong reputation in the chemical industry. Established suppliers typically adhere to stringent quality control measures, ensuring that the tosyl chloride they provide meets the necessary standards.


2. Certifications and Compliance Verify that the supplier complies with industry regulations and standards, such as ISO certifications. This compliance guarantees that the product is manufactured safely and sustainably.


3. Technical Support A reputable supplier should offer technical support, including product specifications, safety data sheets (SDS), and guidance on handling and storage.


4. Pricing and Availability While price is an essential consideration, it should not be the only factor. Ensure that the supplier can maintain a consistent supply and provide competitive pricing without compromising quality.


5. Global Reach For companies operating in multiple regions, sourcing tosyl chloride from suppliers with a global presence can simplify logistics and reduce lead times.


Conclusion


Tosyl chloride (CAS 98-59-9) is a crucial compound in organic chemistry, facilitating various chemical transformations and applications. Understanding its properties and applications can greatly enhance its utility in research and industrial settings. When sourcing this important reagent, it is vital to consider supplier reputation, product quality, and support services to ensure optimal results in your chemical endeavors. Whether you are a researcher in academia or a manufacturer in the industry, having reliable access to tosyl chloride is fundamental for successful projects and innovations.


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