Supplier Information for Tetramisole Hydrochloride (CAS 50586-74-8)

Tetramisole hydrochloride, with the CAS number 50586-74-8, is an anthelmintic agent that is primarily used to treat parasitic infections in animals and humans. Originally introduced as a veterinary drug, its efficacy against various parasites led to its adoption in human medicine, particularly for certain helminth infections. In this article, we will explore the properties, applications, and sourcing options for tetramisole hydrochloride, along with the roles suppliers play in its availability in the market.

Chemical Properties

Tetramisole hydrochloride is a synthetic compound belonging to the imidazothiazole class of chemicals. Its chemical formula is C11H15N3S·HCl, and it has a molecular weight of approximately 241.78 g/mol. The compound appears as a white to off-white crystalline powder and is soluble in water and alcohol, making it versatile for various formulations, including injectables, tablets, and solutions.

The mechanism of action of tetramisole involves the paralysis of helminths through the stimulation of the nematode’s nervous system. This is achieved by interacting with nicotinic acetylcholine receptors, ultimately leading to the expulsion of the parasites from the host's body via peristalsis. Due to this effective mode of action, tetramisole hydrochloride has gained traction in both animal and human health markets.

In veterinary medicine, tetramisole is widely used to treat infections caused by nematodes in livestock such as cattle, sheep, and goats. It is particularly effective against strongyles, ostertagia, and other roundworms that affect the gastrointestinal tract of these animals. The use of tetramisole not only supports the health of livestock but also ensures food safety and quality for consumers.

In human medicine, tetramisole plays a critical role in treating conditions such as ascariasis and hookworm infections. Its application in human healthcare is particularly vital in regions where these parasitic infections are endemic, contributing to improved public health outcomes.

Sourcing and Suppliers

When it comes to acquiring tetramisole hydrochloride, choosing the right supplier is crucial for ensuring product quality and compliance with health regulations. Suppliers of tetramisole hydrochloride typically fall into two categories pharmaceutical manufacturers and chemical distributors.

1. Pharmaceutical Manufacturers These suppliers are primarily involved in the production of medications that contain tetramisole hydrochloride. They adhere to stringent good manufacturing practices (GMP) and regulatory guidelines set by health authorities. It is essential to partner with manufacturers who provide detailed information on the quality testing methods they employ. Many reputable manufacturers also offer Certificates of Analysis (CoA) and other documentation to prove the quality and purity of their products.

2. Chemical Distributors These suppliers specialize in the distribution of a broad range of chemicals, including active pharmaceutical ingredients (APIs) like tetramisole hydrochloride. They typically source their products from reputable manufacturers and provide them to smaller pharmaceutical companies or laboratories. When selecting a chemical distributor, it is important to verify their supply chain practices and ensure they maintain high standards for storage and transport, especially for sensitive compounds.

Conclusion

Tetramisole hydrochloride (CAS 50586-74-8) remains a vital compound in both veterinary and human medicine, with applications extending to the treatment of parasitic infections. When sourcing this important medication, understanding the different types of suppliers available can significantly impact product quality and efficacy. It is imperative to choose suppliers who comply with regulatory standards and can provide adequate documentation of their products.

Whether you are a pharmaceutical company, a veterinarian, or a healthcare provider, ensuring a reliable supply of tetramisole hydrochloride is critical for the effective treatment of parasitic infections. As the demand for this compound grows globally, selecting reputable suppliers will guarantee that you receive a product that meets the necessary safety and quality benchmarks essential for maintaining health and well-being.