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Dec . 07, 2024 03:06 Back to list

china procaine hcl cas 59-46-1



Procaine HCl An Overview of Its Uses and Chemical Characteristics


Procaine hydrochloride, commonly referred to as Procaine HCl, is a local anesthetic agent that has been widely utilized in various medical fields. With the CAS number 59-46-1, it is often recognized for its procedural applications in dentistry, surgery, and pain management. Procaine was first introduced in the early 20th century as a safer alternative to cocaine, which was previously the standard local anesthetic.


Chemical Composition and Properties


Procaine hydrochloride is classified as an esther local anesthetic. Its chemical formula is C13H18N2O2·HCl, and it has a molecular weight of approximately 272.76 g/mol. The structure features a p-aminobenzoic acid derivative, which is crucial to its anesthetic effects. Procaine HCl is typically a white crystalline powder and is soluble in water, making it practical for injectable formulations.


The mechanism of action of Procaine HCl involves blocking sodium channels in neuronal cell membranes, preventing the transmission of nerve impulses. This leads to a loss of sensation in the targeted area. Its onset duration is relatively short and is often used in a combination with other agents to prolong anesthesia.


Clinical Applications

Procaine HCl has a variety of applications in modern medicine. Primarily, it is employed in local anesthesia procedures, allowing patients to undergo surgeries or dental operations with minimal discomfort. In dentistry, it is frequently used during tooth extractions or other oral surgeries, where its ability to provide numbing effects is particularly beneficial.


china procaine hcl cas 59-46-1

china procaine hcl cas 59-46-1

Beyond dental applications, Procaine HCl is also utilized in certain neurological procedures such as nerve blocks or epidural anesthesia. Its versatility makes it suitable for various types of minor surgical interventions across multiple medical specialties.


Furthermore, Procaine has shown some promise in alternative medicine practices. It is sometimes included in bioenergetic therapies, where practitioners claim it can help alleviate chronic pain conditions, although scientific evidence supporting these uses is limited.


Safety and Side Effects


While Procaine HCl is generally considered safe when used correctly, like all medications, it can produce side effects. Common side effects may include allergic reactions, such as skin rashes or itching. Additionally, systemic absorption of Procaine can lead to more serious symptoms, including dizziness, convulsions, or cardiovascular complications.


Healthcare providers must be vigilant regarding the dosage and method of administration to minimize the risk of complications. For patients with a known allergy to ester local anesthetics, alternative agents should be considered.


Conclusion


Procaine hydrochloride remains a significant local anesthetic in contemporary medical practices due to its efficacy and safety profile. With its historical roots and continued usage, it plays an essential role in various procedural applications in medicine. While it is primarily known for its anesthetic properties, ongoing research and discussions in the field of alternative medicine could lead to a broader understanding of its potential benefits. As with any medication, careful consideration of patient history and appropriate dosing is crucial for successful outcomes in clinical settings. Ultimately, Procaine HCl exemplifies the advancements in anesthetic agents, providing effective pain relief for countless procedures since its inception.


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