An Overview of CAS 110-63-4 Manufacturers and Applications

CAS 110-63-4 refers to a chemical compound known as 1,4-Bis(2-hydroxyethyl)piperazine, which plays a vital role in various industrial applications due to its unique chemical properties. Often abbreviated as BHEP, this compound belongs to the family of piperazine derivatives, renowned for their versatile applications in sectors like pharmaceuticals, agriculture, and chemical manufacturing.

Chemical Properties

1,4-Bis(2-hydroxyethyl)piperazine is characterized by its two hydroxyethyl groups attached to the piperazine ring, allowing it to act as a branching agent and crosslinker. This structural arrangement gives it significant solubility in water and organic solvents, facilitating its use in a range of formulations. Its chemical formula is C10H22N2O2, with a molecular weight of approximately 198.30 g/mol.

The compound features a pH-neutral nature, making it suitable for use in sensitive applications, especially in pharmaceuticals and personal care products. Its ability to form stable complexes with metal ions also enhances its utility in varied industrial processes.

Manufacturing Processes

The production of 1,4-Bis(2-hydroxyethyl)piperazine generally involves several steps including the synthesis of piperazine, followed by the reaction of piperazine with ethylene oxide. Manufacturers typically employ controlled conditions to ensure high purity and optimal yield of the final product.

Leading chemical manufacturers often utilize advanced technologies and methodologies to produce CAS 110-63-4. These may include batch synthesis, continuous flow chemistry, or combinatorial chemistry approaches to enhance efficiency and reduce waste. Companies focus on quality control measures, including rigorous testing for chemical purity and consistency, final product performance, and compliance with regulatory standards.

Several manufacturers globally specialize in producing BHEP and related piperazine derivatives. Notable companies in this field include

1. Huntsman Corporation A leading global manufacturer known for specializing in various chemical products, including performance ethyleneamines. 2. BASF One of the largest chemical producers in the world, BASF offers a wide range of specialty chemicals and is involved in synthesizing BHEP for various applications. 3. Dow Chemical Company Another significant player in the chemicals industry, Dow produces a variety of piperazine-related compounds for multiple industrial applications. 4. Fisher Scientific This company provides laboratory chemicals, including BHEP, catering to research and development needs in the scientific community.

These manufacturers have established robust supply chains and distribution networks, ensuring availability of CAS 110-63-4 for different industries.

Applications of BHEP

1. Pharmaceuticals BHEP is commonly utilized as an intermediate in the synthesis of pharmaceutical compounds, particularly those targeting neurological disorders. Its ability to form stable complexes makes it invaluable in drug formulation.

2. Agriculture In agrochemicals, BHEP acts as a surfactant and emulsifier, improving the efficacy of pesticide formulations by enhancing the dispersion of active ingredients.

3. Personal Care Due to its hydrophilic properties and mildness, BHEP is often found in cosmetics and personal care products, where it functions as a conditioning agent.

4. Polymer Industry The compound is also used as a crosslinking agent in the production of polymers, contributing to the enhancement of material properties such as flexibility, strength, and durability.

Conclusion

In summary, CAS 110-63-4 (1,4-Bis(2-hydroxyethyl)piperazine) is a multifaceted compound with applications spanning pharmaceutical, agricultural, and industrial sectors. As manufacturers continue to innovate and improve production processes, the demand for BHEP is expected to grow. The key to staying competitive in this market involves not only producing high-quality products but also adhering to environmental and safety regulations. As such, companies focusing on sustainable practices and product innovation will likely thrive in this dynamic industrial landscape.