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Nov . 02, 2024 03:41 Back to list

bicalutamide cas 90357-06-5



Bicalutamide A Comprehensive Overview


Bicalutamide, a nonsteroidal antiandrogen, is primarily used in the treatment of prostate cancer. This medication, with the CAS (Chemical Abstracts Service) number 90357-06-5, works by blocking the action of androgens, such as testosterone, which can promote the growth of prostate cancer cells. It is commonly prescribed as part of combination therapy, often used in conjunction with other treatments like castration.


Mechanism of Action


Bicalutamide exhibits its therapeutic effects by binding to androgen receptors in the body. By doing so, it inhibits the natural androgens from attaching to these receptors, effectively blocking their action. This prevents the stimulation of growth in androgen-sensitive tissues, including the prostate gland. The result is a decrease in tumor size and a potential reduction in the progression of cancer.


Clinical Usage


The primary indication for bicalutamide is in the treatment of advanced prostate cancer, particularly in patients who are undergoing castration therapy. It is often used as a first-line treatment or to manage prostate cancer that has metastasized. Bicalutamide is also sometimes prescribed for conditions related to hyperandrogenism and other effects of excess androgen levels.


bicalutamide cas 90357-06-5

bicalutamide cas 90357-06-5

Dosage and Administration

Bicalutamide is typically administered orally, with a standard dosage of 50 mg taken once daily. Dosage adjustments may be necessary based on patient response and the severity of side effects. It is essential for patients to adhere to their prescribed regimen for optimal therapeutic outcomes. Patients are advised to consult their healthcare provider for guidance tailored to their specific condition.


Side Effects


While bicalutamide is generally well-tolerated, it is not without its side effects. Common adverse reactions include hot flashes, gastrointestinal disturbances, fatigue, and gynecomastia (enlargement of breast tissue in men). More severe side effects may include liver dysfunction, so regular monitoring of liver function tests is recommended during treatment.


Conclusion


In conclusion, bicalutamide is a critical component in the management of prostate cancer, contributing to improved patient outcomes through its unique mechanism of action. Though side effects may arise, the benefits of effectively targeting androgen receptors make it a valuable tool in oncological therapy. As research continues, the scope of bicalutamide's applications may expand, reinforcing its role in the ongoing battle against prostate cancer. For any individual considering treatment with bicalutamide, a comprehensive discussion with a healthcare professional is imperative to navigate the associated risks and benefits.


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