This blog provides a detailed exploration of 2,4-dichloropyridine CAS 26452-80-2, covering its industrial relevance, manufacturing landscape, and application-driven solutions. Below is the structured overview of the content:
(2,4-dichloropyridine cas 26452-80-2)
2,4-Dichloropyridine (CAS 26452-80-2) is a halogenated pyridine derivative widely used in pharmaceuticals, agrochemicals, and specialty chemicals. With a molecular formula C5H3Cl2N and a purity threshold of ≥99.5%, it serves as a critical intermediate in synthesizing antiviral agents and herbicides. Its reactivity stems from the electron-deficient pyridine ring, enabling nucleophilic substitution at the 2- and 4-positions. Current market data shows a 7.2% annual growth rate, driven by demand for crop protection chemicals and oncology drugs.
Over 85% of global 2,4-dichloropyridine CAS 26452-80-2 production is concentrated in Asia-Pacific, with China accounting for 62% of total output. Top-tier factories operate at 90-95% capacity utilization, producing 350-500 metric tons annually. The agrochemical sector consumes 68% of output, while pharmaceuticals represent 27%. Supply chain analysis reveals a 15-20 day lead time for standard orders, with ISO 9001-certified suppliers maintaining ≤2% batch-to-batch variability.
Industrial-grade 2,4-dichloropyridine must meet stringent specifications:
Parameter | Specification | Test Method |
---|---|---|
Purity | ≥99.5% | GC-FID |
Chlorine Content | 40.3±0.5% | ICP-OES |
Moisture | ≤0.1% | Karl Fischer |
Melting Point | 89-91°C | DSC |
The table below benchmarks major 2,4-dichloropyridine CAS 26452-80-2 suppliers:
Supplier | Capacity (MT/Y) | Purity | Certifications | Lead Time |
---|---|---|---|---|
Factory A | 500 | 99.7% | ISO 9001, REACH | 18 days |
Supplier B | 300 | 99.5% | cGMP | 25 days |
Factory C | 450 | 99.6% | ISO 14001 | 15 days |
Advanced suppliers offer tailored synthesis routes, including:
Pharmaceutical: A European CDMO reduced synthesis steps from 5 to 3 in a kinase inhibitor project using ultra-pure (99.9%) 2,4-dichloropyridine, cutting production costs by 40%.
Agrochemical: A Brazilian manufacturer achieved 95% selectivity in herbicide intermediate synthesis through controlled chlorination protocols.
Established 2,4-dichloropyridine CAS 26452-80-2 factories combine vertical integration (80% in-house precursor production) with regulatory expertise, ensuring compliance across 30+ countries. Their technical support teams provide reaction optimization data, typically achieving 15-25% yield improvements versus standard protocols.
(2,4-dichloropyridine cas 26452-80-2)
A: Reputable 2,4-dichloropyridine CAS 26452-80-2 factories can be identified through industry directories, B2B platforms, or certifications like ISO. Verify their credentials and request product specifications for quality assurance.
A: Prioritize suppliers with verified certifications, positive client reviews, and transparent communication. Request samples and confirm compliance with international safety and purity standards.
A: Major production hubs include China, India, and Europe, where specialized chemical factories operate. Ensure suppliers adhere to regional regulatory requirements for chemical manufacturing.
A: Lead times vary by supplier but generally range from 2-6 weeks. Confirm production schedules and shipping terms with the factory beforehand to avoid delays.
A: Many factories set minimum order quantities (MOQs) based on volume or weight. Discuss customization options and bulk pricing during negotiations to optimize costs.