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nov. . 25, 2024 23:40 Back to list

Phenacitin Powder CAS 62-44-2 Supplier and Manufacturing Information



Exploring Phenacetin Powder A Comprehensive Overview of CAS 62-44-2 and Its Factory Production


Phenacetin, chemically known as N-phenetylacetamide, is an organic compound with the CAS number 62-44-2. It was once a widely used analgesic and antipyretic medicine for alleviating pain and reducing fever. Although it has fallen out of favor due to safety concerns, understanding its production and applications remains vital for various scientific and industrial contexts.


Historical Context and Usage


Phenacetin was first synthesized in the late 19th century and was celebrated for its efficacy in treating pain and fever. It was often used in combination with other analgesics, such as aspirin and acetaminophen. However, in the 1980s, it was linked to serious side effects, including potential carcinogenicity and nephropathy, leading to its withdrawal from the market in many countries. Despite this decline in medicinal usage, phenacetin maintains significance in laboratory research and as an intermediate in chemical synthesis.


Chemical Properties and Applications


Phenacetin is a white, crystalline powder that is soluble in organic solvents such as ethanol and chloroform but poorly soluble in water. Its chemical formula is C10H13NO2, and it has a molar mass of 179.22 g/mol. Due to its analgesic properties, phenacetin has been used in research for its role as a model compound in pharmacological studies.


Within laboratories, phenacetin can serve as a precursor in the synthesis of various pharmaceutical intermediates. Researchers often explore its utility in studying drug metabolism and interaction, paving the way for safer and more effective pain-relief medications.


Factory Production of Phenacetin


phenacitin powder cas 62-44-2 factory

Phenacitin Powder CAS 62-44-2 Supplier and Manufacturing Information

The production of phenacetin powder in factories involves several key steps, including raw material sourcing, synthesis, purification, and packaging. Factories typically begin with phenetidine, an aromatic amine compound, which is acetylated to produce phenacetin. The main processes involved can be described as follows


1. Synthesis The acetylation reaction involves heating phenetidine with acetic anhydride or acetic acid in the presence of catalysts. This reaction yields phenacetin along with by-products that must be removed in the subsequent purification stages.


2. Purification The crude phenacetin obtained from the reaction mixture is then purified through crystallization or recrystallization processes. This step ensures a high degree of purity, which is crucial for both industrial and research applications. Quality control measures are employed to maintain stringent standards, often involving techniques such as high-performance liquid chromatography (HPLC) to analyze the product's purity.


3. Packaging and Distribution After purification, the phenacetin powder is carefully formulated and packaged. Manufacturers often produce it in bulk for distribution to research laboratories and industrial clients. Packaging is designed to preserve the integrity of the powder while adhering to safety regulations.


Regulatory Considerations and Safety


Due to its historical implications and potential health risks, the production of phenacetin is subject to strict regulatory oversight. Factories must comply with environmental and safety regulations, including waste disposal and the handling of hazardous materials. Furthermore, safety data sheets (SDS) are provided to ensure proper handling and to inform users of any potential risks associated with its use.


Conclusion


Phenacetin powder, despite its troubled past in medicinal applications, continues to play a role in various chemical research contexts. The production process in factories involves careful synthesis and purification to deliver high-quality material for industrial and laboratory use. Understanding these aspects of phenacetin allows researchers and manufacturers alike to navigate its complexities, ensuring responsible and informed application in their respective fields.


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