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ਅਗਃ . 17, 2024 01:44 Back to list

Hydroxychloroquine Sulfate CAS 747-36-4 Production and Supplier Information Overview



Hydroxychloroquine Sulfate A Comprehensive Overview


Hydroxychloroquine sulfate, known by its CAS number 747-36-4, is a medication that has gained significant attention in recent years, particularly in the context of antiviral research and treatment for chronic illnesses. This article aims to provide a comprehensive overview of hydroxychloroquine sulfate, including its mechanisms of action, manufacturing processes, and its role in contemporary medicine.


What is Hydroxychloroquine Sulfate?


Hydroxychloroquine is an antimalarial drug that is chemically related to chloroquine. It is primarily used to treat and prevent malaria and to manage autoimmune conditions such as rheumatoid arthritis and lupus erythematosus. The sulfate form of hydroxychloroquine enhances its solubility and stability, facilitating its use in pharmaceutical formulations.


Mechanism of Action


The therapeutic effects of hydroxychloroquine are attributed to its ability to interfere with the lysosomal activity in cells. By increasing the pH within the lysosomes, hydroxychloroquine alters the processing of various proteins and inhibits the activation of immune responses, which is beneficial in autoimmune diseases. Additionally, it is thought to inhibit viral replication by interfering with the entry of viruses into cells and modulating the immune system's response.


Manufacturing Process


The production of hydroxychloroquine sulfate is carried out in specialized pharmaceutical factories adhering to stringent Good Manufacturing Practices (GMP). The manufacturing process typically involves


1. Synthesis of Raw Materials It starts with the synthesis of the active pharmaceutical ingredient (API) through a series of organic reactions. Precursors and solvents are carefully selected and controlled to ensure purity and safety.


2. Formulation Development Once the API is synthesized, it is formulated into dosage forms such as tablets or injectables. This phase includes the selection of excipients that aid in drug stability, bioavailability, and ease of use.


hydroxychloroquine sulfate cas747-36-4 factory

hydroxychloroquine sulfate cas747-36-4 factory

3. Quality Control Rigorous testing is conducted at various stages of production. This includes testing for potency, purity, and contaminants, ensuring the final product meets regulatory standards set by health authorities globally.


4. Packaging and Distribution After quality assurance, the products are packaged in a manner that protects them from light, moisture, and contamination, ready for distribution to pharmacies and healthcare providers.


Hydroxychloroquine in Contemporary Medicine


In recent years, hydroxychloroquine sulfate has been thrust into the spotlight in discussions surrounding the treatment of viral infections, most notably COVID-19. Initial evaluations suggested potential antiviral properties; however, subsequent studies have yielded mixed results regarding its efficacy against SARS-CoV-2, the virus responsible for COVID-19.


Despite the controversies, hydroxychloroquine remains a cornerstone in the treatment of certain autoimmune diseases. Its anti-inflammatory properties provide symptom relief for patients suffering from these chronic conditions, improving their quality of life.


Safety and Side Effects


Like all medications, hydroxychloroquine is not without its risks. Common side effects include gastrointestinal disturbances, headache, and dizziness. More severe reactions can occur, such as retinal toxicity with prolonged use. Thus, it is vital for healthcare providers to monitor patients closely and perform regular eye examinations for those on long-term therapy.


Conclusion


Hydroxychloroquine sulfate continues to be an important therapeutic agent in both infectious disease and autoimmunity management. Its production in GMP-compliant facilities ensures that patients receive high-quality medications. As ongoing research continues to explore its diverse applications and mechanism of action, hydroxychloroquine remains a relevant topic in contemporary medical discourse. The journey of hydroxychloroquine sulfate from the factory to patient care exemplifies the intricacies of pharmaceutical development and the dynamic nature of drug evaluation in real-world settings.


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