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Nov . 18, 2024 10:59 Back to list

Oseltamivir Phosphate CAS 20204255-11-8 Supplier Information and Manufacturing Details



Understanding Oseltamivir Phosphate CAS Number 204255-11-8 and Its Manufacturers


Oseltamivir phosphate, known by its CAS number 204255-11-8, is an antiviral medication primarily used to treat and prevent influenza A and B. It is especially vital during flu seasons and pandemics, where rapid and effective treatment can significantly impact health outcomes. This article will delve into the significance of oseltamivir phosphate, its mechanism of action, and the major manufacturers globally.


Mechanism of Action


Oseltamivir is a prodrug that is converted in the liver to its active form, oseltamivir carboxylate. The active compound inhibits the influenza virus neuraminidase, an enzyme crucial for the viral replication cycle. By blocking this enzyme, oseltamivir prevents the virus from spreading within the respiratory tract, thereby reducing the severity and duration of flu symptoms if administered within the first few days of illness.


Usage Guidelines


Oseltamivir phosphate is typically prescribed for patients who are at least two weeks old. It is recommended for individuals displaying flu symptoms and for those at high risk of flu-related complications, such as the elderly or those with underlying health conditions. Additionally, oseltamivir can be utilized as a preventive measure in individuals exposed to the virus, further highlighting its importance in controlling influenza outbreaks.


Global Manufacturers of Oseltamivir Phosphate


The production of oseltamivir phosphate is a complex process requiring adherence to strict pharmaceutical manufacturing standards. Several key manufacturers around the world are recognized for producing high-quality oseltamivir phosphate.


1. Roche As the original developer of oseltamivir, Roche holds a significant position in the market. Their brand, Tamiflu, is one of the most well-known formulations of oseltamivir phosphate, widely used in both hospitals and outpatient settings.


cas 204255-11-8 oseltamivir phosphate manufacturer

cas 204255-11-8 oseltamivir phosphate manufacturer

2. Hetero Labs Based in India, Hetero is a significant manufacturer of generic pharmaceuticals, including oseltamivir phosphate. They produce the medication at a competitive cost, contributing to the accessibility of antiviral medications in developing countries.


3. Mylan Pharmaceuticals Mylan, now a part of Viatris, has a notable presence in the generic pharmaceutical market, producing oseltamivir phosphate under various branding. Their formulations are commonly used in different regions, ensuring millions have access to treatment.


4. Sandoz A division of Novartis, Sandoz specializes in generic and biosimilar medicines. They are recognized for their robust supply chain and production capabilities, offering oseltamivir phosphate in multiple markets, enhancing competition and availability.


5. Zydus Cadila This Indian multinational pharmaceutical company also plays a critical role in the production of oseltamivir phosphate. They focus on innovation and quality, making their products reliable for both domestic and international health systems.


Importance of Quality Control


Given the critical role of oseltamivir phosphate in public health, it is essential that manufacturers maintain high standards of quality control. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA), impose strict guidelines to ensure the efficacy and safety of pharmaceutical products. This oversight is crucial, as poor-quality drugs can lead to ineffective treatment and contribute to the proliferation of resistant virus strains.


Conclusion


Oseltamivir phosphate (CAS 204255-11-8) is an essential antiviral drug in managing influenza. With key manufacturers like Roche, Hetero Labs, and Mylan, the global supply of this vital medication remains robust. As influenza viruses continue to evolve, ongoing monitoring and research are necessary to ensure the effectiveness of treatments and to prepare for potential outbreaks. The collaboration between pharmaceutical companies and regulatory agencies plays a fundamental role in safeguarding public health, enabling timely access to effective medications like oseltamivir phosphate.


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