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Nov . 24, 2024 10:28 Back to list

wholesale amorolfine hydrochloride cas 78613-38-4



Wholesale Amorolfine Hydrochloride (CAS 78613-38-4) An Overview


Amorolfine hydrochloride, recognized by its CAS number 78613-38-4, is an antifungal agent primarily utilized for the treatment of superficial fungal infections, particularly those affecting the nails. This compound has gained popularity in the pharmaceutical market due to its effective mechanism of action, safety profile, and ease of application, making it a preferred choice among healthcare professionals and patients alike.


Mechanism of Action


Amorolfine operates by disrupting the synthesis of ergosterol, a critical component of fungal cell membranes. By inhibiting the enzyme 14-alpha-demethylase, which is essential for converting lanosterol to ergosterol, amorolfine effectively destabilizes the cell membrane of fungi. This action not only prevents the growth of the fungi but also leads to their eventual cell death. As a result, amorolfine is particularly effective against dermatophytes, yeasts, and non-dermatophyte molds.


Therapeutic Uses


Primarily, amorolfine hydrochloride is indicated for the treatment of onychomycosis, a condition characterized by fungal infection of the nails. It is also used for other superficial fungal infections, such as tinea pedis (athlete's foot) and tinea corporis (ringworm). The formulation of amorolfine is typically available in nail lacquer form, which allows for direct application to the infected nail and surrounding skin. This localized treatment approach not only enhances the drug's efficacy but also minimizes systemic exposure.


Advantages of Amorolfine Hydrochloride


1. Wide Spectrum of Activity Amorolfine is effective against a broad range of fungi, making it a versatile option for treating various fungal infections.


wholesale amorolfine hydrochloride cas 78613-38-4

wholesale amorolfine hydrochloride cas 78613-38-4

2. Patient Compliance The nail lacquer formulation is user-friendly and promotes higher compliance rates among patients. It is applied once or twice weekly, which is convenient compared to some oral antifungal treatments that may require daily administration.


3. Minimal Side Effects Amorolfine has a favorable safety profile. Local side effects, such as minor irritation or allergic reactions, are rare and typically resolve quickly once treatment is discontinued.


4. No Systemic Effects Being applied topically, amorolfine minimizes the risk of systemic side effects commonly associated with oral antifungal medications. This mitigates concerns for vulnerable populations, such as those with liver problems or immunocompromised individuals.


Market Demand and Wholesale Opportunities


Due to its effectiveness and convenience, the demand for amorolfine hydrochloride has surged in recent years. As healthcare providers seek reliable solutions for managing fungal infections, wholesalers have significant opportunities to supply pharmacies, clinics, and hospitals with this desirable compound.


Wholesale purchasing of amorolfine can offer cost benefits, allowing suppliers to stock up and provide competitive pricing to end users. Moreover, as guidelines for treating fungal infections continue to evolve, the importance of reliable and effective treatments like amorolfine will only increase.


Conclusion


In conclusion, amorolfine hydrochloride (CAS 78613-38-4) stands out as a powerful and practical option for the treatment of fungal infections, particularly onychomycosis. Its effective mechanism of action, ease of application, and favorable safety profile make it an integral part of antifungal therapy. With growing awareness and demand for effective treatments, the wholesale supply of amorolfine hydrochloride presents an excellent opportunity for businesses in the pharmaceutical sector to meet the needs of healthcare providers and patients alike. As the market continues to evolve, amorolfine remains a crucial player in the ongoing fight against fungal infections.


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