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Aug . 28, 2024 10:24 Back to list

High-Quality Tosyl Chloride (CAS 98-59-9) Supplier | Reliable Chemical Solutions



Tosyl chloride, also known as p-toluenesulfonyl chloride, is a versatile reagent widely used in organic chemistry. With the CAS number 98-59-9, it is characterized by its sulfonyl group attached to a toluene framework. This compound is particularly valued for its ability to activate alcohols for nucleophilic substitution and to form various derivatives, making it an essential tool in synthetic organic chemistry.


As a supplier of tosyl chloride, it is important to highlight its applications and significance in laboratory settings. Tosyl chloride is commonly employed for the conversion of alcohols into tosylates, which are better leaving groups in subsequent reactions. This property has made tosyl chloride a critical reagent in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.


One of the primary advantages of using tosyl chloride is its ability to enhance the reactivity of alcohols. In a typical procedure, the alcohol is reacted with tosyl chloride in the presence of a base, leading to the formation of the corresponding tosylate. This transformation allows for smoother reactions with nucleophiles such as amines or thiols, facilitating the formation of more complex structures.


Beyond its role in alcohol activation, tosyl chloride can also be utilized in the synthesis of sulfonamides, which have significant biological activity. The transformation of amines into sulfonamides via tosylation is another noteworthy use, showcasing the versatility of this reagent. Additionally, the reactivity of tosyl chloride allows for the introduction of various functional groups through substitution reactions.


tosyl chloride cas 98-59-9 supplier

tosyl chloride cas 98-59-9 supplier

When selecting a supplier for tosyl chloride, several factors should be considered. The quality and purity of the reagent are paramount, as impurities can lead to side reactions and affect the overall yield of the desired product. Reliable suppliers will provide detailed certificates of analysis (CoA) that outline the compound's specifications and purity levels.


In addition to quality, the availability of technical support and guidance is also important. A knowledgeable supplier can assist chemists in optimizing their reactions and troubleshooting issues that may arise during experimental procedures.


In conclusion, tosyl chloride (CAS 98-59-9) is an invaluable reagent in organic synthesis. Its ability to facilitate complex transformations and enhance the reactivity of alcohols makes it a staple in many laboratories. When sourcing tosyl chloride, it is essential to choose a reputable supplier who can ensure product quality and provide necessary support for successful applications in chemical research and industry.


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