Diethyl(Phenylacetyl)malonate An Overview and Suppliers
Diethyl(phenylacetyl)malonate, with the CAS number 20320-59-6, is an organic compound classified under malonic acid derivatives. This compound features a diethyl malonate backbone and a phenylacetyl substituent, making it an important intermediate in various organic synthesis processes. Its distinctive structure contributes to its utility in the field of pharmaceuticals and agrochemicals, where it serves as a versatile building block for the synthesis of more complex molecules.
Chemical Structure and Properties
The chemical structure of diethyl(phenylacetyl)malonate consists of two ethyl ester groups attached to a malonic acid core, along with a phenylacetyl group. This configuration provides unique reactivity patterns, especially in condensation reactions and other transformations applicable in synthetic organic chemistry. Typically, diethyl(phenylacetyl)malonate appears as a colorless to pale yellow liquid with a pleasant odor. Its solubility in organic solvents makes it easy to incorporate into various chemical processes.
Application in Organic Synthesis
One of the main applications of diethyl(phenylacetyl)malonate is in the construction of complex organic molecules through multi-step synthesis. It is often employed in the synthesis of pharmaceuticals where chirality is crucial, aiding in the production of optically active compounds. Additionally, it is utilized in the synthesis of dyes, fragrances, and agrochemicals due to its versatile reactivity.
The compound can undergo reactions such as condensation, hydrolysis, and esterification, allowing chemists to build diverse molecular architectures. Its ability to undergo *Michael addition*, for instance, provides pathways to synthesize larger frameworks found in natural products and medicinal compounds.
Suppliers of Diethyl(Phenylacetyl)malonate
As industrial demand for diethyl(phenylacetyl)malonate continues to grow, several chemical suppliers globally have begun to offer this compound
. When sourcing this reagent, it's important to consider reliability, purity levels, and safety data sheets (SDS) provided by suppliers.1. Specialty Chemical Suppliers Many specialty chemical companies focus on providing high-purity organic compounds for research and industrial applications. Suppliers often provide detailed information on pricing, packaging, and minimum order quantities, helping customers make informed purchasing decisions.
2. Online Chemical Marketplaces Platforms like Sigma-Aldrich, Thermo Fisher Scientific, and others list diethyl(phenylacetyl)malonate among their offerings. These websites typically feature comprehensive catalogs that include pricing and availability, assisting researchers and companies in locating the necessary materials.
3. Local Distributors Depending on your region, local chemical distributors may offer diethyl(phenylacetyl)malonate. These distributors can provide faster shipping times and localized support, making them suitable options for small businesses and academic institutions.
4. Custom Synthesis Companies For specialized requirements or larger quantities, custom synthesis services can be a valuable resource. Companies that provide tailored synthesis can create diethyl(phenylacetyl)malonate to meet specific purity or quantity needs, thereby facilitating research and development.
Conclusion
Diethyl(phenylacetyl)malonate is a valuable compound in the world of organic chemistry, serving as a crucial intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialized chemicals. With a variety of suppliers available—from large multinational companies to local distributors—there is ample opportunity for researchers and manufacturers to source this compound effectively. Understanding both its properties and the market landscape for this compound ensures informed decision-making for all stakeholders in the chemical manufacturing industry.