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Oct . 13, 2024 16:51 Back to list

phenacitin powder cas 62-44-2 factory



Phenacitin Powder An Overview of CAS 62-44-2 and Its Manufacturing Process


Phenacitin, known scientifically as 4-ethoxyacetanilide, is a chemical compound with the CAS number 62-44-2. It has a unique profile that makes it valuable in various applications, particularly in the pharmaceutical industry, where it has historically been used as an analgesic and antipyretic agent. Although its use has declined in recent years due to safety concerns, phenacitin remains a subject of interest in chemical research and manufacturing.


Chemical Structure and Properties


The molecular formula of phenacitin is C10H13NO2, and its structure features an ethoxy group attached to an acetanilide backbone. This combination endows it with specific chemical characteristics, including solubility in organic solvents and moderate stability under typical storage conditions. Understanding these properties is crucial for manufacturers aiming to produce high-quality phenacitin powder.


Manufacturing Process

The production of phenacitin powder typically involves several key steps. The primary raw materials used are acetanilide and ethyl iodide. The manufacturing process begins with the alkylation of acetanilide with ethyl iodide in the presence of a base, often in a solvent like acetone. This reaction leads to the formation of phenacitin, which is then purified through various methods such as recrystallization.


Recrystallization not only enhances the purity of the final product but also helps to achieve the desired particle size and morphology, critically important for its applications. The purification process often employs solvents like ethanol or methanol, where the crude product is dissolved, and impurities are removed by filtration. Once crystallized, the phenacitin powder is dried to eliminate any remaining moisture, ensuring that the final product meets industry specifications.


phenacitin powder cas 62-44-2 factory

phenacitin powder cas 62-44-2 factory

Quality Control


Quality control is a fundamental aspect of the manufacturing process. Manufacturers adhere to strict guidelines to ensure that the phenacitin powder produced is of the highest quality. This includes testing for purity, identifying possible contaminants, and assessing the physical properties of the powder. Techniques such as High-Performance Liquid Chromatography (HPLC) and Infrared Spectroscopy (IR) are commonly employed to ascertain the compound's identity and purity.


Applications and Market Demand


Phenacitin's primary historical application was as a pain reliever and fever reducer; however, its use in human medicine has significantly decreased due to safety concerns linked to its metabolite, which can cause methemoglobinemia (a condition that affects the blood’s ability to carry oxygen). Consequently, the market demand for phenacitin has shifted, focusing on its use in research, where it serves as a reference compound or an intermediate in the synthesis of other chemical entities.


Conclusion


While phenacitin (CAS 62-44-2) is no longer a mainstream pharmaceutical agent, the manufacturing processes associated with this compound offer valuable insights into chemical production and quality assurance. As the industry evolves, understanding how to efficiently produce and utilize such compounds is essential for researchers and chemists alike. The complexities of its production, coupled with ongoing studies regarding its chemical properties and potential applications, ensure that phenacitin remains relevant in certain scientific circles. As we advance, its legacy serves as a reminder of the delicate balance between the efficacy and safety of chemical compounds in therapeutic use.


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