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Sep . 22, 2024 14:12 Back to list

phenacitin powder cas 62-44-2



Phenacetin, a compound with the chemical formula C10H13NO2, is an analgesic and antipyretic agent that historically played a significant role in the treatment of pain and fever. With the CAS number 62-44-2, it became well-known in the pharmaceutical industry during the late 19th century. As a white crystalline powder, phenacetin was widely used as an over-the-counter medication, often found in combination with other active ingredients to enhance its therapeutic effects.


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Despite its effectiveness, the use of phenacetin declined in the latter part of the 20th century due to safety concerns. Studies indicated that prolonged usage could lead to serious side effects, including renal damage and an increased risk of certain cancers. In particular, the association between phenacetin and nephropathy—a condition characterized by kidney damage—raised alarms in medical communities, leading to a reevaluation of its safety profile.


phenacitin powder cas 62-44-2

phenacitin powder cas 62-44-2

Consequently, many countries began to restrict or ban the use of phenacetin in pharmaceutical preparations. Alternative analgesics, such as paracetamol (acetaminophen) and nonsteroidal anti-inflammatory drugs (NSAIDs), gained popularity due to their improved safety records and efficacy. Despite its official ban in certain regions, phenacetin remains of interest in research settings for its historical significance and chemical properties.


Today, phenacetin is not widely available as an over-the-counter drug, but it is still utilized in some laboratory settings for research purposes. Scientists examine its metabolic pathways and interactions, contributing to a better understanding of pain mechanisms and drug toxicity.


In summary, the story of phenacetin illustrates the complex relationship between therapeutic benefits and the potential for adverse effects in pharmaceutical development. Although it largely disappeared from common practice, its legacy continues to impact the development of safer alternatives and highlights the importance of ongoing monitoring of drug safety profiles throughout their usage.


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