Exploring Phenacetin CAS 62-44-2 and Its Suppliers

Phenacetin, designated by its Chemical Abstracts Service (CAS) number 62-44-2, is an analgesic and antipyretic compound that has garnered attention in both the pharmaceutical and chemical industries. Once widely used as a pain reliever and fever reducer, its usage has declined due to safety concerns. Despite this, it remains a compound of interest for research and specialty applications. In this article, we will delve into the properties and applications of phenacetin, while also exploring its suppliers in the market.

Properties of Phenacetin

Phenacetin is an organic compound belonging to the class of chemicals known as analgesics. It is synthesized through the acetylation of phenetidine, an aniline derivative. The molecular formula of phenacetin is C_10H_13N_O_2, and it typically appears as a white crystalline powder. It is relatively soluble in organic solvents but has limited solubility in water.

The compound acts by inhibiting the production of prostaglandins, which are compounds involved in the inflammatory response and pain sensation. This mechanism provides relief from various types of pain, including headaches, muscle aches, and dental pain. However, due to its association with adverse effects, such as renal damage and the potential for carcinogenicity, phenacetin was banned in many countries by the late 20th century for use in over-the-counter medications.

Current Applications

Despite the safety concerns, phenacetin still has applications in specific sectors. It is primarily used in laboratory research and the synthesis of other chemical compounds. Many researchers utilize it in the study of pain mechanisms and the development of alternative analgesics. Additionally, its chemical properties make it useful in synthesizing dyes, plastics, and various other chemical compounds.

Furthermore, phenacetin is deployed in certain industrial processes and may serve as an intermediate in the production of pharmaceuticals. Its unique properties make it valuable in organic synthesis, particularly in the synthesis of acetaminophen, a widely used pain reliever and fever reducer.

Finding reliable suppliers of phenacetin can be challenging, particularly due to its restricted usage in many regions. However, several chemical and pharmaceutical companies continue to manufacture and supply phenacetin for research and industrial purposes. Here is a list of potential suppliers

1. Sigma-Aldrich A part of the Merck Group, Sigma-Aldrich is one of the leading suppliers of chemicals for research and laboratory applications. They provide high-purity phenacetin suitable for various research purposes.

2. Alfa Aesar Alfa Aesar, a Thermo Fisher Scientific brand, offers a wide range of chemicals, including phenacetin. They supply it in various quantities, catering to both small-scale research and larger industrial needs.

3. TCI Chemicals TCI (Tokyo Chemical Industry Co., Ltd.) specializes in fine chemicals, and they offer phenacetin as a part of their extensive catalog. Their products are often used in academic and industrial research settings.

4. Acros Organics Acros Organics is known for providing high-quality laboratory chemicals. Their supply of phenacetin can be useful for researchers engaged in organic synthesis and pharmaceutical development.

5. Chemsamp LLC This supplier focuses on providing a variety of specialty chemicals, including phenacetin. They are known for custom synthesis and offering tailored solutions for specific industrial applications.

Conclusion

Phenacetin, with its CAS number 62-44-2, represents a unique compound with a rich historical significance and contemporary relevance in research and industrial applications. While its use as a medication has declined due to safety concerns, it serves as an essential tool in scientific exploration and chemical synthesis. Suppliers such as Sigma-Aldrich, Alfa Aesar, TCI Chemicals, Acros Organics, and Chemsamp LLC continue to provide access to this compound, ensuring that it remains a part of the chemical landscape for those pursuing research and development in various fields. As regulations evolve and research advances, the future of phenacetin may open new avenues for its application in safe and innovative ways.