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Nov . 23, 2024 14:35 Back to list

phenacetin cas 62-44-2 manufacturer



Phenacetin An Overview of Its Manufacturer and Applications


Phenacetin, chemically known as N-(4-ethoxyphenyl)acetamide, is an analgesic and antipyretic agent historically used in various medicinal formulations. With the CAS number 62-44-2, this compound has been a significant player in the pharmaceutical industry for decades. However, due to its association with various health risks, its use has diminished over the years. In this article, we will explore the manufacturers of phenacetin, its historical significance, and its applications.


Historical Background


Phenacetin was first synthesized in the mid-19th century and became widely used in the early to mid-20th century. It was known for its effectiveness in relieving pain and reducing fever, making it a popular choice for chronic pain management and fevers. Produced primarily in pharmaceutical laboratories, it was often combined with other analgesics in formulations.


Despite its initial popularity, the health risks associated with phenacetin began to surface in the late 20th century. Studies indicated that long-term use could lead to adverse effects such as kidney damage and an increased risk of cancer. As a result, many countries began to restrict its use, leading pharmaceutical companies to reformulate their products, dissociating from phenacetin altogether.


Manufacturers of Phenacetin

As demand for phenacetin declined, the number of manufacturers also decreased. Today, manufacturers of phenacetin primarily focus on the production of pharmaceutical-grade chemicals, catering to specific markets that still require this compound for various applications. These companies adhere to stringent regulatory requirements to ensure product safety and efficacy.


phenacetin cas 62-44-2 manufacturer

phenacetin cas 62-44-2 manufacturer

Prominent manufacturers of phenacetin can be found mainly in countries with robust pharmaceutical industries, including the United States, China, and India. These companies not only produce phenacetin but also engage in research and development to explore alternative uses for the compound or to create safer alternatives.


Most manufacturers prioritize quality control, adhering to Good Manufacturing Practices (GMP) and ensuring compliance with regulations set forth by authorities such as the FDA and European Medicines Agency (EMA). This focus on quality is crucial, particularly as the industry moves towards an emphasis on safety and sustainability.


Applications of Phenacetin


Despite the controversies surrounding its use, phenacetin still finds applications in specific domains. It plays a role in the production of certain laboratory reagents, offering utility in chemical research. Additionally, it has been utilized in veterinary medicine and in certain formulations that require its analgesic properties.


Its role in the pharmaceutical landscape has shifted from direct consumer use to being a functional ingredient for manufacturers aiming to create specialized products. Research into alternatives has also led to the development of safer derivatives and new compounds that provide similar therapeutic benefits without the associated risks.


Conclusion


In summary, phenacetin (CAS 62-44-2) has a complex history marked by both its usefulness and the health risks it poses. While its popularity has waned significantly, manufacturers continue to produce this compound for niche applications in the pharmaceutical industry. The focus on regulatory compliance and quality assurance among manufacturers is vital in ensuring the safe use of phenacetin in the pharmaceutical realm. As the industry evolves, the exploration of safer alternatives remains a priority, paving the way for innovations in pain management and fever reduction while prioritizing patient safety.


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