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Aug . 13, 2024 06:46 Back to list

Find Reliable Suppliers for 2,4-Dichloropyridine CAS 26452-80-2 Chemical Products



2,4-Dichloropyridine A Key Intermediate in Organic Synthesis


2,4-Dichloropyridine, a chemical compound with the CAS number 26452-80-2, is an important intermediate in organic synthesis and pharmaceutical production. This heterocyclic aromatic compound, consisting of a pyridine ring substituted with two chlorine atoms at the 2 and 4 positions, has gained attention for its diverse applications in various fields, including agrochemicals, pharmaceuticals, and materials science.


Structure and Properties


The molecular formula of 2,4-dichloropyridine is C5H3Cl2N, and its molecular weight is approximately 162.99 g/mol. The presence of chlorine atoms in the pyridine ring not only enhances the compound's reactivity but also contributes to its unique physical and chemical properties. 2,4-Dichloropyridine is typically a colorless to yellow liquid with a characteristic odor. It has a boiling point of about 179°C and is moderately soluble in water, but more soluble in organic solvents like ether and ethanol.


Synthesis


2,4-Dichloropyridine can be synthesized through various methods, including the chlorination of pyridine itself or through more complex multi-step synthetic routes involving different reagents and catalysts. One common approach involves the reaction of pyridine with phosphorus pentachloride (PCl5) or sulfuryl chloride (SO2Cl2) under controlled conditions to selectively introduce chlorines at the desired positions on the aromatic ring.


Applications


The applications of 2,4-dichloropyridine span several industries. In the agrochemical sector, it serves as a precursor for the synthesis of various herbicides and pesticides, which target specific weeds while minimizing environmental impact. The compound's chlorinated nature enhances its biological activity, making it effective in controlling unwanted vegetation.


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Find Reliable Suppliers for 2,4-Dichloropyridine CAS 26452-80-2 Chemical Products

In the pharmaceutical industry, 2,4-dichloropyridine is utilized as an intermediate in the synthesis of various therapeutic agents. Its reactive chlorine atoms can undergo nucleophilic substitutions, facilitating the incorporation of different functional groups that lead to the development of diverse pharmaceuticals, including anti-infectives and anti-inflammatory drugs.


Moreover, the chemical is employed in the production of specialty chemicals and materials. Its ability to participate in various organic reactions, such as nucleophilic aromatic substitution and cross-coupling reactions, makes it valuable for creating complex organic compounds that serve in both research and industrial applications.


Safety and Environmental Considerations


While 2,4-dichloropyridine is a valuable chemical in many respects, it is crucial to handle it with care due to its potential hazards. The compound is classified as harmful and may cause respiratory irritation and skin sensitivity. As such, appropriate safety measures, including the use of personal protective equipment (PPE), are essential when working with this substance.


Furthermore, environmental considerations are paramount, especially regarding the disposal of any waste that may contain 2,4-dichloropyridine. Regulatory guidelines must be followed to limit the impact on ecosystems and human health. Manufacturers and suppliers of 2,4-dichloropyridine are responsible for adhering to these regulations and ensuring that their practices prioritize safety and environmental protection.


Conclusion


In summary, 2,4-dichloropyridine is a significant compound with critical roles in various sectors, particularly in the synthesis of agrochemicals and pharmaceuticals. Its unique properties and reactivity make it a valuable intermediate in organic synthesis. However, the potential risks associated with its handling necessitate rigorous safety protocols. As research and industrial applications expand, the demand for compounds like 2,4-dichloropyridine is likely to grow, underscoring the importance of sustainable practices in chemical manufacturing.


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