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Aug . 09, 2024 08:05 Back to list

Diethyl phenylacetylmalonate CAS 20320-59-6 supplier and manufacturing information for chemical industry applications



Diethyl(Phenylacetyl)malonate A Comprehensive Overview


Diethyl(phenylacetyl)malonate, commonly known by its CAS number 20320-59-6, is an important organic compound widely utilized in various fields, including pharmaceuticals, agrochemicals, and synthetic organic chemistry. This compound has garnered attention due to its unique chemical structure and versatile reactivity, making it a valuable building block for the synthesis of a variety of complex molecules.


Chemical Structure and Properties


Diethyl(phenylacetyl)malonate consists of a malonate core where two ethyl groups are esterified to one carboxylic acid, and one of the hydrogen atoms is replaced by a phenylacetyl group. This combination of esters and acyl groups not only imparts interesting chemical properties but also enhances its solubility in organic solvents, making it easier to work with in synthetic reactions.


The molecular formula of diethyl(phenylacetyl)malonate is C13H16O4, and it has a molecular weight of approximately 236.26 g/mol. This compound exhibits a moderate boiling point and is generally stable under standard laboratory conditions. Its reactivity profile allows it to participate in various chemical transformations, including condensation reactions, acylation, and as a Michael donor in conjugate addition reactions.


Applications in Organic Synthesis


In the realm of organic synthesis, diethyl(phenylacetyl)malonate is primarily used as a versatile intermediate for the production of more complex molecules. For example, it can be employed in the synthesis of dihydropyridine derivatives that have significant pharmaceutical activity, including anti-hypertensive and anti-oxidant properties.


Moreover, the malonate moiety provides a useful scaffold for the introduction of multiple functional groups, allowing chemists to customize the resulting compounds for specific activities. This adaptability makes it a popular choice in both academic research and industrial applications.


diethyl(phenylacetyl)malonate cas 20320-59-6 factory

diethyl(phenylacetyl)malonate cas 20320-59-6 factory

Pharmaceutical Importance

The pharmaceutical industry has recognized the potential of diethyl(phenylacetyl)malonate in drug design and development. Several derivatives of this compound exhibit biological activities that are of interest to medicinal chemists. For example, the compound can be modified to enhance its efficacy, selectivity, and bioavailability, paving the way for the development of new therapeutic agents.


Furthermore, due to its structural similarity to other biologically active molecules, researchers often use diethyl(phenylacetyl)malonate as a starting material to devise new drug candidates or to improve existing ones. Its role in the synthesis of enzyme inhibitors, receptor ligands, and anti-cancer agents is well-documented.


Manufacturing and Availability


As the demand for diethyl(phenylacetyl)malonate grows, numerous manufacturers worldwide have started producing this compound, catering to the needs of researchers and companies in the pharmaceutical and agrochemical sectors. These factories adhere to stringent quality control measures to ensure the purity and consistency of the product, crucial for downstream applications.


When sourcing diethyl(phenylacetyl)malonate, it is essential to choose reliable suppliers who provide comprehensive product specifications, such as purity levels, batch numbers, and safety data. The availability of this compound in various quantities, ranging from research scale to bulk production, further enhances its appeal to diverse users.


Conclusion


In conclusion, diethyl(phenylacetyl)malonate is a significant compound in the realm of organic chemistry, particularly for its role in pharmaceutical synthesis. Its unique structure, reactivity, and applications make it a valuable asset in the field of drug discovery and development. As research progresses and more applications are discovered, the importance and utility of diethyl(phenylacetyl)malonate are set to expand, reinforcing its position as a key player in modern synthetic chemistry.


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