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Nov . 22, 2024 16:39 Back to list

china procaine hcl cas 59-46-1



Procaine HCl An Overview of Its Properties and Applications


Procaine hydrochloride, commonly known by its chemical formula C13H18N2O2.HCl and its CAS number 59-46-1, is an important local anesthetic that has been widely used in medical practices since its introduction in the early 20th century. This compound is an ester of para-aminobenzoic acid and is primarily employed in various medical procedures to provide localized anesthesia, thus ensuring pain-free experiences for patients undergoing surgery or dental work.


Chemical Structure and Properties


Procaine HCl is characterized by its molecular structure, which includes an aromatic ring and an aliphatic amine. This configuration is responsible for its pharmacological properties. As a hydrochloride salt, procaine HCl is more stable and soluble in water, making it suitable for injection and other applications. The compound typically appears as a white crystalline powder and is odorless, with a slightly bitter taste. It is readily soluble in water and slightly soluble in alcohol, positioning it as an effective agent in various aqueous formulations for injection.


Mechanism of Action

The primary function of procaine HCl is to block nerve conduction by inhibiting the influx of sodium ions through voltage-gated sodium channels in the neuronal cell membrane. By doing so, it prevents the transmission of pain signals to the brain, allowing for effective localized anesthesia. Its relatively short duration of action makes procaine suitable for minor surgical procedures where prolonged anesthesia is not required. This quick onset and duration of action have made procaine a popular choice among healthcare providers.


Clinical Applications


china procaine hcl cas 59-46-1

china procaine hcl cas 59-46-1

Procaine HCl is predominantly used in dentistry, where it is often employed during dental procedures to numb specific areas of the mouth. It is also utilized in minor surgical interventions and regional anesthesia. In addition to its use in healthcare, procaine has been explored in other fields, including veterinary medicine, where it serves a similar purpose for animal procedures.


However, its use has evolved over the years, with newer anesthetic agents offering improved efficacy and safety profiles. Despite this, procaine HCl remains a relevant option in specific scenarios, particularly in outpatient settings or for patients with certain contraindications to other anesthetics.


Safety and Side Effects


While procaine HCl is generally considered safe when administered correctly, potential side effects can occur. These may include allergic reactions, skin irritation, or systemic toxicity if large doses are administered improperly. Medical practitioners must adhere strictly to dosage guidelines to minimize these risks. An important consideration is the observation for any signs of allergic reactions, particularly in individuals who have a history of sensitivities to local anesthetics.


Conclusion


Procaine hydrochloride, with its long-standing role in the medical field as a local anesthetic, continues to play a significant part in ensuring patient comfort during various procedures. Understanding its properties, mechanism of action, and appropriate applications is crucial for healthcare professionals to effectively utilize this compound. As the landscape of anesthetic agents evolves, procaine remains a testament to the advancements in medicine and the constant pursuit of patient safety and comfort.


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