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Nov . 22, 2024 07:20 Back to list

china phenacitin powder cas 62-44-2



Exploring Phenetidin Properties, Uses, and Safety Concerns


Phenetidin, also known by its CAS number 62-44-2, is an organic compound that belongs to the class of aniline derivatives. Structurally, it is an aromatic amine that has been utilized in various applications, such as in pharmaceuticals and as a chemical intermediate. This compound, which has a molecular formula of C8H10N2O, plays a crucial role in the synthesis of dyes, drugs, and other chemical products.


Properties of Phenetidin

Phenetidin is a crystalline powder that is white to light yellow in appearance. Its melting point is around 56°C, and it has a boiling point of approximately 200°C. The compound is slightly soluble in water but readily soluble in organic solvents such as ethanol and ether. This solubility profile makes it a versatile candidate for various chemical reactions and applications.


One of the notable properties of phenetidin is its role as a precursor in the synthesis of acetaminophen (paracetamol), which is widely used for its analgesic and antipyretic effects. Phenetidin and its derivatives have been extensively studied for their potential therapeutic roles and the development of new pharmaceuticals.


Uses in Pharmaceuticals


Phenetidin has historically been used in the formulation of various medications, particularly those designed to alleviate pain and reduce fever. Its transformation into acetaminophen highlights its significance in medicinal chemistry. Acetaminophen is one of the most commonly consumed over-the-counter pain relievers globally, praised for its efficacy and relative safety compared to other analgesics like aspirin.


Moreover, phenetidin has been utilized in the production of antihistamines and antipyretic agents. The pharmaceutical industry continually explores its derivatives for potential new drug formulations, making phenetidin a compound of ongoing interest.


china phenacitin powder cas 62-44-2

china phenacitin powder cas 62-44-2

Safety and Toxicology


Despite its utility, phenetidin is not without risks. It has been associated with potential toxic effects, particularly when used improperly. Prolonged exposure to high concentrations can lead to methemoglobinemia, a condition in which hemoglobin is unable to effectively carry oxygen, leading to cyanosis and other health complications.


Additionally, the compound has been linked to kidney damage and other adverse effects when consumed inappropriately or in high doses. Users of products containing phenetidin must adhere to recommended usage guidelines to mitigate these risks. Regulatory bodies closely monitor its use in pharmaceuticals to ensure safety and efficacy, especially given its association with serious health issues.


Regulatory Status


Phenetidin's regulatory status varies by country, with some regions imposing strict controls on its use due to its potential health risks. In many jurisdictions, it is categorized as a controlled substance, and its production and sale are regulated to prevent misuse and ensure safety in its applications.


Conclusion


Phenetidin (CAS 62-44-2) is an important compound in the field of medicinal chemistry, with significant applications in pharmaceuticals. Its role as a precursor to acetaminophen highlights its relevance in pain management and fever reduction. However, it is essential to recognize the safety concerns associated with its use. Continued research and regulatory oversight are necessary to ensure that the benefits of phenetidin can be harnessed while minimizing potential risks to public health. As the pharmaceutical landscape evolves, phenetidin remains a compound of interest in the pursuit of new therapeutic agents and the safe use of existing drugs.


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