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Dec . 26, 2024 13:53 Back to list

china 4,7-dichloroquinoline cas 86-98-6



4,7-Dichloroquinoline Properties, Applications, and Safety Considerations


4,7-Dichloroquinoline, with the Chemical Abstracts Service (CAS) number 86-98-6, is a synthetic organic compound belonging to the quinoline family. This heterocyclic compound features a dual chlorine substitution at the 4 and 7 positions of the quinoline ring, leading to significant impacts on its chemical properties and biological activities. The structure of 4,7-dichloroquinoline makes it an intriguing subject of study within the realms of chemistry and pharmacology.


Chemical Properties


The chemical formula of 4,7-dichloroquinoline is C9H6Cl2N, and its molecular weight is approximately 203.06 g/mol. It is characterized by a yellowish crystalline appearance and possesses a relatively stable structure under standard laboratory conditions. The presence of chlorine atoms enhances its electrophilic characteristics, enabling it to participate in a variety of chemical reactions, including nucleophilic substitutions and oxidative reactions. Such properties make it a valuable intermediate in the synthesis of more complex organic molecules.


Synthesis


4,7-Dichloroquinoline can be synthesized through several methods, including halogenation of quinoline and other related compounds. Researchers often explore diverse synthetic routes to enhance yields and optimize reaction conditions. The synthesis of this compound is of interest not only for chemical research but also for potential applications in medicinal chemistry.


Biological Activity


The biological activities of 4,7-dichloroquinoline have been a subject of research, particularly in its potential as an antimalarial and antimicrobial agent. Quinoline derivatives are known for their ability to combat Plasmodium species, the parasites responsible for malaria. The modifications introduced by the chlorine substituents can influence the affinity of the compound for biological targets, improving its efficacy in medicinal applications.


china 4,7-dichloroquinoline cas 86-98-6

china 4,7-dichloroquinoline cas 86-98-6

Research has shown that derivatives of quinoline, including 4,7-dichloroquinoline, exhibit antitumor properties. The compound's mechanism of action is believed to involve the inhibition of key enzymes and interference with cellular processes in cancer cells. As a result, 4,7-dichloroquinoline and its derivatives are explored as potential candidates in anticancer drug development.


Applications in Industry


In addition to its pharmaceutical potential, 4,7-dichloroquinoline has applications in the production of dyes and pigments due to its synthetic versatility and stable chromatic properties. The compound can also be utilized in the development of various agrochemicals, including herbicides and insecticides. The ability to modify its structure allows chemists to tailor its properties for specific applications in different areas of industry.


Safety and Handling


While 4,7-dichloroquinoline has demonstrated promising biological activity, safety considerations are paramount when handling this compound. It is essential to consult relevant Material Safety Data Sheets (MSDS) to understand its toxicity and recommended handling procedures. Safety measures should include the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Additionally, working within a well-ventilated fume hood is advisable to minimize inhalation exposure.


Conclusion


4,7-Dichloroquinoline, represented by CAS number 86-98-6, offers a fascinating glimpse into the world of organic chemistry with its unique structure, diverse applications, and potential therapeutic benefits. As research continues to unfold regarding its properties and uses, 4,7-dichloroquinoline holds promise not only in medicinal chemistry but also in industrial applications. Safe handling and further studies will be essential to unlocking its full potential in various fields.


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