The Chemical Profile of 4-Fluoro-3-Methylphenol (CAS 452-70-0)
4-Fluoro-3-methylphenol, with the CAS number 452-70-0, is an organic compound that plays a crucial role in various industrial applications. This aromatic compound features both a hydroxyl group (-OH) and a fluorine atom attached to a methyl-substituted phenolic structure, contributing to its unique chemical properties and reactivity.
Chemically, 4-Fluoro-3-methylphenol is recognized for its potential use as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The presence of both the hydroxyl and fluorine groups enhances the molecule's ability to participate in various chemical reactions, making it a valuable building block in organic synthesis. The fluorine atom can significantly influence the compound's lipophilicity and biological activity, allowing researchers to design molecules with improved efficacy and reduced toxicity.
Physical and Chemical Properties
This compound typically appears as a colorless to light yellow liquid or solid, depending on the conditions. Its melting point is around 26-28 °C, while its boiling point is approximately 185 °C. The molecular formula of 4-Fluoro-3-methylphenol is C7H7FO, with a molecular weight of about 144.13 g/mol. The compound is relatively soluble in organic solvents like ethanol and ether, but it possesses limited solubility in water.
Applications
The primary applications of 4-Fluoro-3-methylphenol are found in the pharmaceutical industry, where it serves as a precursor for various drug molecules. For instance, its structural features allow for modifications that lead to the synthesis of pharmaceutical agents targeting a range of medical conditions. Additionally, its derivatives can act as antimicrobial agents, adding to its significance in the field of medicine.
In agrochemicals, 4-Fluoro-3-methylphenol and its derivatives contribute to the development of herbicides and pesticides, enhancing crop protection while maintaining ecological balance. The introduction of fluorine into chemical compounds often improves their stability and effectiveness, making them desirable in a competitive agrochemical market.
Safety and Handling
Like many chemicals, 4-Fluoro-3-methylphenol must be handled with care. It is advisable to use appropriate personal protective equipment (PPE) such as gloves and goggles when working with this compound to prevent skin and eye contact. Safety data sheets (SDS) should be consulted to understand better its hazards, including potential irritation or environmental impact.
In conclusion, 4-Fluoro-3-methylphenol (CAS 452-70-0) represents an important chemical entity in both organic synthesis and applied science. As demand for effective pharmaceutical and agrochemical compounds continues to grow, the significance of such versatile intermediates is poised to increase. Understanding its properties, applications, and safe handling practices is essential for professionals working in the chemical and pharmaceutical industries.