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Dec . 04, 2024 09:34 Back to list

cas 23076-35-9 xylazine hydrochloride



Xylazine Hydrochloride An Overview


Xylazine hydrochloride, identified by its CAS number 23076-35-9, is a pharmaceutical agent primarily used as a sedative, analgesic, and muscle relaxant in veterinary medicine. Initially developed for use in animals, particularly horses, its applications have expanded over time, including use in various species, both domesticated and wild.


As a member of the alpha-2 adrenergic agonist class, xylazine functions by binding to alpha-2 receptors in the central nervous system (CNS). This binding results in a decrease in neurotransmitter release, providing its sedative and analgesic effects. The drug is often used during surgical procedures to induce sedation and as a pre-anesthetic agent to facilitate smoother anesthetic induction and recovery.


Medical Uses and Administration

In veterinary practice, xylazine hydrochloride is administered via injection, typically intramuscularly or intravenously. Its onset of action is rapid, usually taking effect within minutes, which is particularly beneficial in emergency situations where quick sedation is necessary. The duration of effect varies depending on the dosage and specific formulation used, generally lasting anywhere from 30 minutes to several hours.


Apart from its primary use in surgery, xylazine is also applied in various diagnostic and therapeutic procedures that require patient immobilization. For instance, it’s often employed in veterinary dentistry, imaging studies like radiography, and in the treatment of certain stress-related conditions in animals.


Side Effects and Precautions


cas 23076-35-9 xylazine hydrochloride

cas 23076-35-9 xylazine hydrochloride

While xylazine is useful in clinical settings, it is essential to consider its side effects and contraindications. Common adverse effects include bradycardia (slow heart rate), respiratory depression, decreased body temperature, and sensitivity to stimuli. More severe reactions can occur, particularly in overdose situations, which could lead to significant cardiovascular collapse or death.


Because of these potential side effects, careful dosing and monitoring are crucial, especially in patients with pre-existing health conditions or those receiving concurrent medications. Vets must assess each animal’s unique circumstances, including breed, age, and overall health status, before administration.


Xylazine in Human Medicine


Interestingly, while xylazine was initially restricted to veterinary use, there have been reports of illicit human use, particularly among certain drug-user populations. Its increasing occurrence in combination with opioids presents significant public health concerns. Notably, xylazine is often used due to its sedative properties, though its presence in the human drug supply poses severe risks. The potential for overdose and the physiological dangers associated with xylazine can lead to complications that are difficult to manage without specific antidotes.


Additionally, xylazine is not approved for human use by regulatory authorities such as the Food and Drug Administration (FDA) in the United States. This status emphasizes the need for public awareness regarding the dangers of unregulated substances often found in illicit drug markets.


Conclusion


In summary, xylazine hydrochloride is a valuable medication in veterinary medicine, offering sedation, analgesia, and muscle relaxation for a range of procedures. However, its associated risks and potential for misuse underscore the importance of responsible management and application of the drug. Continued research and vigilance are essential to mitigate the risks associated with both therapeutic use in animals and the consequences of unregulated use in humans. As veterinary practices evolve and the landscape of drug use changes, understanding the properties, benefits, and dangers of xylazine hydrochloride remains vital for healthcare professionals and the wider community.


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