Exploring the Manufacturer of Pregabalin CAS 20148553-50-8

Pregabalin, identified by the Chemical Abstracts Service (CAS) number 20148553-50-8, is a pharmaceutical compound widely recognized for its role in treating neuropathic pain, epilepsy, and generalized anxiety disorder. As an analogue of gamma-aminobutyric acid (GABA), pregabalin exerts its therapeutic effects by modulating calcium channel activity, thereby inhibiting the release of excitatory neurotransmitters. Given its clinical significance, the role of reputable manufacturers in producing high-quality pregabalin is crucial. This article delves into the importance of these manufacturers and how they contribute to the availability and efficacy of this important medication.

The manufacturing of pharmaceutical products, particularly those intended for central nervous system disorders like pregabalin, requires stringent quality control measures. Manufacturers must comply with Good Manufacturing Practices (GMP) as outlined by regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). These regulations ensure that every batch of pregabalin produced is safe, effective, and of the highest quality.

Quality assurance begins with the selection of raw materials. Manufacturers of pregabalin must source high-purity intermediates that will be used in the synthesis of the drug. In addition, they must maintain meticulous records throughout the production process, including stringent testing of both raw materials and finished products. Such protocols are essential to minimize the risk of contaminants, impurities, or deviations from the prescribed formulation.

Leading Manufacturers of Pregabalin

Several pharmaceutical companies worldwide are known for their production of pregabalin. Among them, well-established firms often have robust research and development (R&D) departments that focus on enhancing drug formulations and delivery methods. These companies invest in the latest technologies and innovations to improve the efficacy and patient compliance of their medications.

One prominent manufacturer is Pfizer, which introduced pregabalin to the market under the brand name Lyrica. Pfizer has played a significant role in the research, development, and commercialization of pregabalin, ensuring that it meets the rigorous standards of patient care. Their ongoing commitment to clinical trials and patient safety showcases the importance of responsible manufacturing practices.

In addition to pharmaceutical giants, there are numerous generic manufacturers that produce pregabalin. These companies contribute to making the drug more accessible and affordable to a broader population. Generic manufacturers must adhere to the same GMP standards as their brand-name counterparts, ensuring that their products are equivalent in quality and efficacy.

Addressing Market Needs

The demand for pregabalin has seen a significant rise due to its wide-ranging applications. Neuropathic pain, particularly associated with conditions such as diabetes and shingles, has become increasingly prevalent in populations. Furthermore, the rising incidence of anxiety disorders has propelled pregabalin to the forefront of mental health treatment. As a result, manufacturers are continuously working to scale their production capabilities to meet this growing demand.

Moreover, the emergence of online pharmacies and international markets has led to an increase in the availability of pregabalin. In response, manufacturers must ensure that their distribution channels maintain the integrity of the drug throughout the supply chain. This includes protecting the medication from improper storage conditions and allowing for transparent tracking of batches from production to dispensing.

Conclusion

Pregabalin, with CAS number 20148553-50-8, plays a vital role in modern medicine for managing pain and anxiety. The responsibility of manufacturers in producing this drug is paramount, as their adherence to quality standards directly impacts patient health outcomes. With ongoing innovations and regulatory compliance, reputable manufacturers ensure that pregabalin remains an effective and accessible option for those in need. As healthcare evolves, the commitment of these manufacturers to excellence will undoubtedly continue to shape the future of pain and mental health management.