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Nov . 12, 2024 21:53 Back to list

cas 148553-50-8 pregabalin



Pregabalin, with the chemical abstract service (CAS) number 148553-50-8, is a medication primarily used to treat neuropathic pain, epilepsy, and generalized anxiety disorder. Originally developed as an anticonvulsant, pregabalin is well-known for its ability to modulate the release of certain neurotransmitters in the brain, particularly by binding to the alpha-2-delta subunit of voltage-gated calcium channels. This mechanism of action makes it particularly effective in reducing the sensation of pain and controlling seizures.


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In addition to its role in pain management, pregabalin is also utilized as an adjunct therapy for adults with partial onset seizures. It is particularly beneficial for patients who may not respond adequately to other anticonvulsants. The efficacy of pregabalin in controlling seizures has been supported by numerous clinical trials, showing that it can effectively reduce the frequency of seizure episodes.


cas 148553-50-8 pregabalin

cas 148553-50-8 pregabalin

Moreover, pregabalin has gained attention for its anxiolytic effects. It is prescribed for patients with generalized anxiety disorder (GAD), where it can help reduce feelings of excessive worry and anxiety. This application is especially important, as untreated anxiety can significantly impair an individual’s daily functioning and overall well-being.


Despite its benefits, pregabalin is not without potential side effects. Common side effects include dizziness, sleepiness, and peripheral edema. Patients are advised to start on a low dose and gradually increase it to minimize these effects. Additionally, it is essential for healthcare providers to monitor patients for signs of dependency or misuse, particularly given pregabalin's potential for abuse in some populations.


In conclusion, pregabalin (CAS 148553-50-8) is a versatile medication with applications in the treatment of neuropathic pain, epilepsy, and anxiety disorders. Its unique mechanism of action and favorable efficacy profile make it an important tool in modern medicine, improving the lives of many patients struggling with chronic pain and anxiety-related conditions.


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