Overview of 4,7-Dichloroquinoline CAS 86-98-6

4,7-Dichloroquinoline (CAS Number 86-98-6) is a compound that has garnered significant attention in various sectors, such as pharmaceuticals, agrochemicals, and material science. The quinoline backbone is a well-studied structure in organic chemistry, known for its diverse biological activities. The introduction of chlorine atoms at the 4 and 7 positions of the quinoline ring enhances its potential applications, making it a compound of interest for both researchers and industrial manufacturers.

Chemical Properties

4,7-Dichloroquinoline can be described as a pale-yellow crystalline solid, characterized by its distinct chemical properties. With a molecular formula of C9H5Cl2N, the compound displays a molecular weight of approximately 202.05 g/mol. The presence of chlorine atoms contributes to its chemical reactivity, allowing it to engage in various reactions that can be exploited in synthetic chemistry. Furthermore, its relatively low melting point and solubility in organic solvents make it suitable for numerous applications.

The industrial production of 4,7-dichloroquinoline typically involves several synthetic routes that balance yield, cost, and environmental concerns. One of the most common methods involves the chlorination of quinoline, where chlorinating agents such as thionyl chloride or phosphorus oxychloride are used. This reaction requires careful control of temperature and reaction conditions to ensure the desired dichlorinated product is obtained while minimizing by-products. Manufacturers are increasingly focusing on sustainable practices, reducing waste, and optimizing processes to achieve greener production methods.

Applications

The applications of 4,7-dichloroquinoline are diverse and impactful across multiple industries.

1. Pharmaceuticals Due to its structural features, 4,7-dichloroquinoline is studied for its potential as a pharmaceutical agent. It exhibits antimicrobial, antifungal, and anti-inflammatory properties, making it a candidate for drug development in treating various infections and diseases. Researchers continue to investigate its efficacy, structure-activity relationships, and mechanisms of action to better understand its pharmaceutical potential.

2. Agrochemicals In the agricultural sector, 4,7-dichloroquinoline can be employed as a herbicide or biocide, helping to control pests and weeds in crops. Its effectiveness in managing agricultural challenges contributes to increased yield and food security. As sustainable agriculture practices grow, the need for innovative agrochemicals, including compounds like 4,7-dichloroquinoline, is becoming more pronounced.

3. Material Science 4,7-Dichloroquinoline is also explored in the field of materials science, particularly in the development of specialized polymers and electronic materials. Its unique chemical properties facilitate the creation of materials with specific characteristics suitable for advanced applications, including sensors, coatings, and conductive materials.

Safety and Regulatory Considerations

Given its potential for biological activity, the safety and handling of 4,7-dichloroquinoline are critical concerns in both industrial and laboratory settings. It is essential for manufacturers and researchers to adhere to safety regulations and guidelines established by authorities such as the Environmental Protection Agency (EPA) and the Occupational Safety and Health Administration (OSHA). Proper personal protective equipment (PPE) should be used when handling the compound, and appropriate waste disposal methods must be followed to mitigate environmental impact.

Conclusion

In conclusion, 4,7-dichloroquinoline (CAS 86-98-6) presents a rich area of exploration within the realms of chemistry, biology, and material science. Its significant applications in pharmaceuticals, agrochemicals, and advanced materials highlight its versatility as a compound. As research advances and industrial practices evolve, the potential of 4,7-dichloroquinoline may contribute to breakthroughs in health, agriculture, and technology, demonstrating the enduring value of this chemical compound in modern society. Manufacturers continue to innovate and improve the production of this compound in a sustainable manner, ensuring its continued relevance in an ever-evolving world.