Phenacetin is recognized by its distinctive CAS number 62-44-2 and is primarily noted for its historical use in pharmaceuticals. This white, crystalline powder was once a common component in pain relief medications but has since been discontinued in numerous jurisdictions due to concerns about its safety profile. Understanding the implications and characteristics of phenacetin powder is crucial for professionals working with chemical compounds or those in the pharmaceutical industry.

Dating back to its initial use in the late 19th century, phenacetin rose to prominence as a fever reducer and painkiller, benefiting countless individuals suffering from conditions like arthritis and neuralgia. Its ability to alleviate pain without causing stomach irritation made it a preferred choice over aspirin for some time. The primary mechanism through which phenacetin operates involves its conversion into paracetamol (acetaminophen) within the body. This conversion allows it to impart analgesic and antipyretic effects efficiently.
However, it became apparent in the latter half of the 20th century that prolonged usage of phenacetin could lead to significant health complications, including nephropathy, a type of kidney damage. These health concerns led to its removal from the market in several countries, including the United States and Canada, by the early 1980s. Despite these withdrawals, phenacetin has retained interest within certain chemical research circles where it is studied for its properties and potential applications outside conventional medicine.

phenacitin powder cas 62-44-2
For individuals and businesses considering the purchase or use of phenacetin powder, it's paramount to source this compound from reputable suppliers who can provide certification of analysis (COA) and material safety data sheets (MSDS). The importance of adhering to these safety protocols cannot be overstated, as the compound is subject to strict regulations in many regions. Ensuring transparency and accuracy in sourcing allows for trust in the product and minimizes the risk of encountering substandard or unsafe materials.
In modern times, phenacetin continues to appear in various research scenarios, driving interest due to its unique chemical characteristics. Researchers are exploring potential new applications that can leverage its legacy without compromising safety. While phenacetin is not used in mainstream pharmaceutical applications today, its relevance persists in niche research and development projects aiming to unlock new insights into pain management and chemical synthesis.
It's critical for any contemporary discussion around phenacetin to be framed within the context of safety and responsibility. Professionals engaging with this compound should do so with an acute awareness of its history and the pivotal shift towards safer, more effective analgesics that followed its decline in use. By maintaining a steadfast commitment to ethical research practices and transparent information exchange, the study of phenacetin powder can continue to contribute valuable insights without endangering public health.