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Dec . 10, 2024 16:50 Back to list

3-chloropyridine cas 626-60-8



3-Chloropyridine A Comprehensive Overview


3-Chloropyridine, with the Chemical Abstracts Service (CAS) number 626-60-8, is an essential compound in the field of organic chemistry. It belongs to the family of chlorinated pyridines, which are derivatives of pyridine that have chlorine atoms substituted for hydrogen. This particular isomer of chloropyridine is characterized by the presence of a chlorine atom at the third position on the pyridine ring.


Chemical Structure and Properties

The chemical formula of 3-chloropyridine is C5H4ClN, indicating that it is composed of five carbon atoms, four hydrogen atoms, one chlorine atom, and one nitrogen atom. The presence of the nitrogen atom in the heterocyclic structure contributes to its unique properties and reactivity. As a colorless to pale yellow liquid, 3-chloropyridine has a boiling point of approximately 165 degrees Celsius and a density of around 1.157 g/cm³. It is soluble in organic solvents such as ethanol and ether, which makes it versatile for various chemical reactions.


Synthesis


3-Chloropyridine can be synthesized through several methods, one of which involves the chlorination of pyridine. This process can be achieved through electrophilic aromatic substitution, where chlorine is introduced to the aromatic ring under specific conditions. Another approach involves the use of pyridine derivatives as precursors, which can be chlorinated at the desired position using chlorinating agents. The choice of method often depends on the desired yield, purity, and economic considerations.


Applications


3-chloropyridine cas 626-60-8

3-chloropyridine cas 626-60-8

3-Chloropyridine plays a significant role in various industrial applications and research fields. One of its main uses is as a building block in the synthesis of pharmaceutical compounds, where it contributes to the development of drugs with diverse biological activities. It has been employed in the synthesis of agrochemicals, including herbicides and fungicides, making it valuable for agricultural applications.


In addition to its role in pharmaceuticals and agrochemicals, 3-chloropyridine serves as an intermediate in the production of various specialty chemicals. Its ability to undergo further reactions, such as nucleophilic substitutions, enables the formation of more complex molecules. The compound's functional properties also make it a candidate for use in materials science, particularly in the development of new polymers and molecular materials.


Toxicity and Safety


While 3-chloropyridine has useful applications, it is essential to handle this compound with care due to its toxicity. It can cause irritation to the skin, eyes, and respiratory system, and prolonged exposure may lead to more severe health effects. Therefore, appropriate safety measures should be observed during its handling, including the use of personal protective equipment (PPE), adequate ventilation, and following guidelines for chemical waste disposal.


Conclusion


In summary, 3-chloropyridine is a valuable chemical compound with a diverse range of applications in pharmaceuticals, agrochemicals, and materials science. Its unique chemical properties and reactivity make it a critical building block in the synthesis of various organic compounds. As research continues to advance in the fields of chemistry and materials science, the importance of 3-chloropyridine is likely to grow, highlighting the need for careful handling and further investigation into its potential applications. With its multifaceted roles and capabilities, 3-chloropyridine remains a compound of great interest within the scientific community.


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